Methicillin

Base Information Edit

Chemical Name:Methicillin
CAS No.:61-32-5
Deprecated CAS:16983-15-6
Molecular Formula:C17H20N2O6S
Molecular Weight:380.422
Hs Code.:
European Community (EC) Number:205-083-9,200-505-8
UNII:Q91FH1328A
DSSTox Substance ID:DTXSID6023284
Nikkaji Number:J2.341H
Wikipedia:Methicillin
Wikidata:Q409262
NCI Thesaurus Code:C61842
Metabolomics Workbench ID:43590
ChEMBL ID:CHEMBL575
Mol file:61-32-5.mol

Synonyms:Dimethoxyphenyl Penicillin;Methicillin;Methicillin Hydrate, Monosodium Salt;Methicillin Monohydrate, Monosodium Salt;Methicillin Sodium;Meticillin;Metin;Penicillin, Dimethoxyphenyl;Staphcillin

Suppliers and Price of Methicillin

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
MRSA Selective Supplement for microbiology
5 vials
$ 132.00

Sigma-Aldrich
MRSA Selective Supplement for microbiology
5vl
$ 128.00

Total 23 raw suppliers

Chemical Property of Methicillin Edit

Chemical Property:

Vapor Pressure:2.94E-17mmHg at 25°C
Refractive Index:1.638
Boiling Point:640 °C at 760 mmHg
PKA:pKa 2.77± 0.04(H2O,t = 25,c=0.0097) (Uncertain)
Flash Point:340.9 °C
PSA：130.47000
Density:1.44 g/cm³
LogP:1.27790
XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:380.10420754
Heavy Atom Count:26
Complexity:600

Purity/Quality:

98%,99%, ^*data from raw suppliers

MRSA Selective Supplement for microbiology ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C(N2C(S1)C(C2=O)NC(=O)C3=C(C=CC=C3OC)OC)C(=O)O)C
Isomeric SMILES:CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)C3=C(C=CC=C3OC)OC)C(=O)O)C
Recent NIPH Clinical Trials:Development of TDM-guided treatment with daptomycin based on PK/PD theory by measurement of plasma concentration of daptomycin.
Uses Antibacterial.

Technology Process of Methicillin

There total 3 articles about Methicillin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 551-16-6
6-Aminopenicillanic Acid

: 61-32-5
methicillin

Guidance literature:: Multi-step reaction with 2 steps

1: CHCl₃

2: (i) ClCO₂Et, Et₃N, CHCl₃, dioxane, (ii) /BRN= 1082694/

In chloroform;