isosaccharino-1,4-lactone

Base Information

• Chemical Name: isosaccharino-1,4-lactone
• CAS No.: 7397-89-9
• Molecular Formula: C6H10 O5
• Molecular Weight: 162.142
• Mol file: 7397-89-9.mol

Synonyms:Isosaccharinicacid, g-lactone, a-D- (6CI); GISAL; a-D-Glucoisosaccharinic acid g-lactone; a-D-Isosaccharin

Chemical Property of isosaccharino-1,4-lactone

Chemical Property:

• Vapor Pressure: 1.98E-06mmHg at 25°C
• Boiling Point: 354°C at 760 mmHg
• PKA: 12.17±0.40(Predicted)
• Flash Point: 152.9°C
• PSA: 86.99000
• Density: 1.49g/cm³
• LogP: -1.98240

Purity/Quality:

98%Min ^*data from raw suppliers

Isosaccharinic acid-1,4-lactone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Isosaccharinic Acid-1,4-lactone (cas# 7397-89-9) is a useful reagent in the preparation of uranium oxo isosaccharinate isosaccharinatelactone complexes.

Technology Process of isosaccharino-1,4-lactone

There total 3 articles about isosaccharino-1,4-lactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C6H11O6(1-)*Na(1+) → 2-hydroxymethyl-2R,4S,5-trihydroxypentanoic acid-1,4-lactone (7388-79-6) + 3-deoxy-2-C-hydroxymethyl-D-erythro-pentono-1,4-lactone (7397-89-9)

Guidance literature:

With Amberlite-H(+); In water;

DOI:10.1016/j.carres.2011.11.022

Reference yield:

α-isosaccharinic acid (1518-54-3) → 3-deoxy-2-C-hydroxymethyl-D-erythro-pentono-1,4-lactone (7397-89-9)

Guidance literature:

Equilibrium constant;

DOI:10.1023/B:JOSL.0000002988.99769.cb

Reference yield:

→ 3-deoxy-2-C-hydroxymethyl-D-erythro-pentono-1,4-lactone (7397-89-9)

Guidance literature:

aus Lactose;

upstream raw materials:

α-isosaccharinic acid

Downstream raw materials:

(2S,4S)-3-deoxy-2-hydroxymethyl-2¹,5-di-O-p-toluenesulfonyl-D-erythro-pentono-1,4-lactone

2,5,6-tri-O-benzoyl-2-hydroxymethyl-2S,4S,5-trihydroxypentanoic acid-1,4-lactone

4-Nitro-benzoic acid (3S,5R)-3-hydroxy-5-methyl-2-oxo-tetrahydro-furan-3-ylmethyl ester

Refernces

• 1、 Ekberg,Ekberg,Albinsson. "Characterization of α-isosaccharinic acid: Lactone and carboxylic conformations". . p. 465 - 477. Retrieved 2007/10/03.