Azapropazone

Base Information

• Chemical Name: Azapropazone
• CAS No.: 13539-59-8
• Molecular Formula: C16H20 N4 O2
• Molecular Weight: 300.36
• European Community (EC) Number: 236-913-8
• NSC Number: 102824
• UNII: K2VOT966ZI
• DSSTox Substance ID: DTXSID6045408
• Nikkaji Number: J8.123J
• Wikipedia: Azapropazone
• Wikidata: Q368222
• NCI Thesaurus Code: C73074
• Metabolomics Workbench ID: 55747
• ChEMBL ID: CHEMBL1565476
• Mol file: 13539-59-8.mol

Synonyms:5-(Dimethylamino)-9-methyl-2-propyl-1H-pyrazolo(1,2-a)(1,2,4)benzotriazine-1,3(2H)-dione;Apazone;Apazone Dihydrate;Azapropazone;Dihydrate, Apazone;Prolixan;Rheumox;Tolyprin

Chemical Property of Azapropazone

Chemical Property:

• Vapor Pressure: 7.16E-08mmHg at 25°C
• Melting Point: 228°
• Refractive Index: 1.6000 (estimate)
• Boiling Point: 438°Cat760mmHg
• PKA: 8.66±0.20(Predicted)
• Flash Point: 218.7°C
• PSA: 60.13000
• Density: 1.29g/cm³
• LogP: 2.48470
• Water Solubility.: 147.2mg/L(35 oC)
• XLogP3: 4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 300.15862589
• Heavy Atom Count: 22
• Complexity: 516

Purity/Quality:

99% ^*data from raw suppliers

Azapropazone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCC1C(=O)N2C3=C(C=CC(=C3)C)N=C(N2C1=O)N(C)C
• Uses: An anti-inflammatory, analgesic, and antipyretic. It is also useful in the treatment of gout due to its uricosuric actions. Cyclo-oxygenase inhibitor; analgesic; anti-inflammatory.
• Therapeutic Function: Antiarthritic

Technology Process of Azapropazone

There total 1 articles about Azapropazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ azapropazone (13539-59-8)

Guidance literature: