cyclopropyl-hydroxyiminoacetic acid

Base Information

• Chemical Name: cyclopropyl-hydroxyiminoacetic acid
• CAS No.: 936097-37-9
• Molecular Formula: C₅H₇NO₃
• Molecular Weight: 129.115
• Mol file: 936097-37-9.mol

Synonyms:cyclopropyl-hydroxyiminoacetic acid

Chemical Property of cyclopropyl-hydroxyiminoacetic acid

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cyclopropyl-hydroxyiminoacetic acid

There total 2 articles about cyclopropyl-hydroxyiminoacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-cyclopropyl-2-oxo acetate potassium salt (56512-18-6) → cyclopropyl-hydroxyiminoacetic acid (936097-37-9)

Guidance literature:

With hydroxylamine hydrochloride; In water; at 45 ℃; for 0.333333h;

DOI:10.1002/adsc.200606038

Reference yield:

Cyclopropyl methyl ketone (765-43-5) → cyclopropyl-hydroxyiminoacetic acid (936097-37-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 74 percent / KMnO₄; Na₂CO₃ / H₂O / 50 h / 50 °C

2: 99 percent / NH₂OH*HCl / H₂O / 0.33 h / 45 °C

With potassium permanganate; hydroxylamine hydrochloride; sodium carbonate; In water;

DOI:10.1002/adsc.200606038

Reference yield: 93.0%

cyclopropyl-hydroxyiminoacetic acid (936097-37-9) → (S)-2-amino-2-cyclopropyl acetic acid (15785-26-9)

Guidance literature:

With zinc; In acetic acid; at 20 - 30 ℃; for 0.5h;

DOI:10.1002/adsc.200606038

upstream raw materials:

2-cyclopropyl-2-oxo acetate potassium salt

Cyclopropyl methyl ketone

Downstream raw materials:

(S)-2-amino-2-cyclopropyl acetic acid

methyl 2-(N-benzyloxycarbonylamino)-2-cyclopropylacetate

methyl 2-amino-2-cyclopropylacetate

(S)-2-amino-2-cyclopropylacetic acid

Refernces