Boc-D-prolinol

Base Information Edit

Chemical Name:Boc-D-prolinol
CAS No.:83435-58-9
Molecular Formula:C₁₀H₁₉NO₃
Molecular Weight:201.266
Hs Code.:29051990
European Community (EC) Number:626-169-6
DSSTox Substance ID:DTXSID40350854
Nikkaji Number:J1.687.465E
Wikidata:Q72450549
ChEMBL ID:CHEMBL1869411
Mol file:83435-58-9.mol

Synonyms:BOC-D-PROLINOL;83435-58-9;N-Boc-D-prolinol;(R)-tert-butyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate;(R)-(+)-1-Boc-2-pyrrolidinemethanol;tert-butyl (2R)-2-(hydroxymethyl)pyrrolidine-1-carboxylate;1-Boc-D-Prolinol;N-(tert-Butoxycarbonyl)-D-prolinol;(R)-1-BOC-PYRROLIDIN-2-YL-METHANOL;59378-81-3;(R)-(+)-1-(tert-Butoxycarbonyl)-2-pyrrolidinemethanol;MFCD00040580;SMR000857152;N-tert-Butoxycarbonyl-D-prolinol;N-tert-Butoxycarbonyl-D-prolinol,;(R)-Boc-prolinol;Boc-(R)-prolinol;N-t-Boc-D-prolinol;(R)-N-Boc prolinol;N-BOC-D-PRO-OH;(+) N-BOC-D-prolinol;(R)-1-(tert-Butoxycarbonyl)-2-pyrrolidinemethanol;MLS001332407;MLS001332408;SCHEMBL135177;CHEMBL1869411;DTXSID40350854;tert-butyl (R)-2-(hydroxymethyl)pyrrolidine-1-carboxylate;(R)-1-Boc-2-pyrrolidinemethanol;BFFLLBPMZCIGRM-MRVPVSSYSA-N;HMS2231L07;(R)-N-Boc-pyrrolidine-2-methanol;BCP25215;CS-D1199;AKOS005259759;N-Alpha-tert-butoxycarbonyl-D-prolinol;AC-5652;AM83119;NCGC00166099-01;(2R)-(+)-1-Boc-2-pyrrolidinemethanol;BP-13177;DS-14390;HY-78924;B3076;(R)-1-t-butoxycarbonyl-2-pyrrolidinemethanol;(R)-(+)-1-Boc-2-pyrrolidinemethanol, 98%;EN300-153802;N-Boc-D-prolinol, puriss., >=99.0% (TLC);(2R)-N-tert-Butyloxycarbonylpyrrolidin-2-ylmethanol;(R)-1-tert-butoxycarbonyl-2-hydroxymethylpyrrolidine;Q-101619;(R)-(+)-(tert-butoxy-carbonyl)-2-pyrrolidinemethanol;(R)-(+)-1-(t-butoxycarbonyl)-2-pyrrolidinemethanol;t-butyl (R)-2-hydroxymethylpyrrolidine-1-carboxylate;(R)-t-Butyl 2-(hydroxymethyl)-1-pyrrolidinecarboxylate;(R)-tert-butyl (hydroxymethyl)pyrrolidine-1-carboxylate;tert-butyl (R)-2-hydroxymethylpyrrolidine-1-carboxylate;Z1269244172;(R)-tert-Butyl 2-(hydroxymethyl)-pyrrolidine-1-carboxylate;tert-butyl (2R)-2-(hydroxymethyl)-1-pyrrolidinecarboxylate;tert-butyl(2R)-2-(hydroxymethyl)pyrrolidine-1-carboxylate;(R)-2-(hydroxymethyl)pyrrolidine-1-carboxylic acid tert-butyl ester;1,1-dimethylethyl (2R)-2-(hydroxymethyl)-1-pyrrolidinecarboxylate;2-(R)-hydroxymethyl-pyrrolidine-1-carboxylic acid tert-butyl ester;(R)-(+)-2-Hydroxymethyl-pyrrolidine-1-carboxylic acid tert-butyl ester;(R)-2-(hydroxymethyl)-1pyrrolidinecarboxylic acid, 1,1-dimethylethyl ester;(R)-2-HYDROXYMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;2-Methyl-2-propanyl (2R)-2-(hydroxymethyl)-1-pyrrolidinecarboxylate;(R)-2-(hydroxymethyl)-1-pyrrolidinecarboxylic acid, 1,1-dimethylethyl ester;(R)-(+)-1-(tert-Butoxycarbonyl)-2-pyrrolidinemethanol, N-t-Boc-D-prolinol, N-Boc-D-prolinol

Suppliers and Price of Boc-D-prolinol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-(tert-Butoxycarbonyl)-D-prolinol
100 g
$ 545.00

TCI Chemical
N-(tert-Butoxycarbonyl)-D-prolinol >98.0%(GC)
5g
$ 45.00

TCI Chemical
N-(tert-Butoxycarbonyl)-D-prolinol >98.0%(GC)
1g
$ 16.00

SynQuest Laboratories
N-Boc-D-prolinol
25 g
$ 288.00

SynQuest Laboratories
N-Boc-D-prolinol
1 g
$ 56.00

SynQuest Laboratories
N-Boc-D-prolinol
5 g
$ 92.00

Sigma-Aldrich
(R)-(+)-1-Boc-2-pyrrolidinemethanol 98%
1g
$ 66.40

Matrix Scientific
(R)-tert-Butyl 2-(hydroxymethyl)-pyrrolidine-1-carboxylate 95+%
10g
$ 50.00

Matrix Scientific
(R)-tert-Butyl 2-(hydroxymethyl)-pyrrolidine-1-carboxylate 95+%
5g
$ 30.00

Matrix Scientific
(R)-tert-Butyl 2-(hydroxymethyl)-pyrrolidine-1-carboxylate 95+%
1g
$ 21.00

Total 142 raw suppliers

Chemical Property of Boc-D-prolinol Edit

Chemical Property:

Appearance/Colour:white powder
Melting Point:60-64 °C(lit.)
Refractive Index:54 ° (C=5, MeOH)
Boiling Point:289.5 °C at 760 mmHg
PKA:14.77±0.10(Predicted)
Flash Point:128.9 °C
PSA：49.77000
Density:1.084 g/cm₃
LogP:1.31610
Storage Temp.:Store at 0°C
Solubility.:Chloroform (Slightly), Methanol (Slightly)
Water Solubility.:insoluble
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:201.13649347
Heavy Atom Count:14
Complexity:210

Purity/Quality:

99% ^*data from raw suppliers

N-(tert-Butoxycarbonyl)-D-prolinol ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn,Xi
Hazard Codes:Xi,Xn
Statements: 36/37/38-20/21/22
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCCC1CO
Isomeric SMILES:CC(C)(C)OC(=O)N1CCC[C@@H]1CO
Uses N-(tert-Butoxycarbonyl)-D-prolinol is used to prepare (azetidinyl)methoxy]pyridines and 2-(aryloxymethyl) azacyclic analogs with therapeutic potetials for the treatment of central nervous system (CNS) disorders.

Technology Process of Boc-D-prolinol

There total 16 articles about Boc-D-prolinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%