C₂₁H₂₄F₂O₆

Base Information

• Chemical Name: C₂₁H₂₄F₂O₆
• CAS No.: 1413373-44-0
• Molecular Formula: C₂₁H₂₄F₂O₆
• Molecular Weight: 410.415
• Mol file: 1413373-44-0.mol

Synonyms:C₂₁H₂₄F₂O₆

Chemical Property of C₂₁H₂₄F₂O₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₁H₂₄F₂O₆

There total 22 articles about C₂₁H₂₄F₂O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

C49H48F2O6 (1413373-42-8) → C21H24F2O6 (1413373-44-0)

Guidance literature:

With hydrogenchloride; hydrogen; palladium 10% on activated carbon; In tetrahydrofuran; methanol; water; at 20 ℃; for 1h;

Reference yield:

2,3,4,6-Tetra-O-benzyl-D-glucopyranose (4291-69-4,6386-24-9,6564-72-3,59531-24-7,69257-52-9,78184-89-1,78609-16-2,78609-17-3,78609-18-4,96553-53-6,104111-61-7,131347-08-5,4132-28-9) → C21H24F2O6 (1413373-44-0)

Guidance literature:

Multi-step reaction with 10 steps

1.1: toluene; tetrahydrofuran / 3.67 h / 0 - 50 °C / Inert atmosphere

2.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 1.25 h / -78 - -40 °C / Inert atmosphere

2.2: 2.25 h / -78 - 20 °C

3.1: L-proline / dimethyl sulfoxide / 8 h / 50 °C

4.1: pyridine; trichlorophosphate / 0 - 20 °C

5.1: L-Selectride / tetrahydrofuran / 18 h / 0 - 20 °C / Inert atmosphere

5.2: 0.25 h

6.1: 1,1'-azodicarbonyl-dipiperidine; tributylphosphine / toluene / 0.5 h / 0 °C / Inert atmosphere

7.1: dimethylsulfide borane complex / tetrahydrofuran / 0 - 20 °C

7.2: 3 h / 0 - 20 °C

8.1: Dess-Martin periodane / dichloromethane / 3 h / 0 - 20 °C

9.1: diethylamino-sulfur trifluoride / dichloromethane / 20 °C / Inert atmosphere

10.1: hydrogenchloride; hydrogen / palladium 10% on activated carbon / water; tetrahydrofuran; methanol / 1 h / 20 °C

With pyridine; hydrogenchloride; oxalyl dichloride; tributylphosphine; diethylamino-sulfur trifluoride; dimethylsulfide borane complex; hydrogen; L-Selectride; Dess-Martin periodane; dimethyl sulfoxide; L-proline; 1,1'-azodicarbonyl-dipiperidine; trichlorophosphate; palladium 10% on activated carbon; In tetrahydrofuran; methanol; dichloromethane; water; dimethyl sulfoxide; toluene; 6.1: Mitsunobu reaction;

Reference yield:

methoxybenzene (100-66-3) → C21H24F2O6 (1413373-44-0)

Guidance literature:

Multi-step reaction with 7 steps

1.1: pyrographite; methanesulfonic acid / 12 h / 80 °C

2.1: hydrogen / palladium 10% on activated carbon / ethanol / 22502.3 Torr

3.1: 1,1'-azodicarbonyl-dipiperidine; tributylphosphine / toluene / 0.5 h / 0 °C / Inert atmosphere

4.1: dimethylsulfide borane complex / tetrahydrofuran / 0 - 20 °C

4.2: 3 h / 0 - 20 °C

5.1: Dess-Martin periodane / dichloromethane / 3 h / 0 - 20 °C

6.1: diethylamino-sulfur trifluoride / dichloromethane / 20 °C / Inert atmosphere

7.1: hydrogenchloride; hydrogen / palladium 10% on activated carbon / water; tetrahydrofuran; methanol / 1 h / 20 °C

With hydrogenchloride; methanesulfonic acid; tributylphosphine; diethylamino-sulfur trifluoride; dimethylsulfide borane complex; hydrogen; pyrographite; Dess-Martin periodane; 1,1'-azodicarbonyl-dipiperidine; palladium 10% on activated carbon; In tetrahydrofuran; methanol; ethanol; dichloromethane; water; toluene; 3.1: Mitsunobu reaction;

upstream raw materials:

ortho-anisaldehyde

methoxybenzene

2,3,4,6-Tetra-O-benzyl-D-glucopyranose

salicylic acid

Refernces