1-Chloroethyl isopropyl carbonate

Base Information

• Chemical Name: 1-Chloroethyl isopropyl carbonate
• CAS No.: 98298-66-9
• Molecular Formula: C6H10ClO3
• Molecular Weight: 166.605
• Hs Code.: 2920909090
• Mol file: 98298-66-9.mol

Synonyms:1-(Isopropyloxycarbonyloxy)ethylchloride;Isopropyl 1-chloroethyl carbonate;a-Chloroethyl isopropyl carbonate;

Chemical Property of 1-Chloroethyl isopropyl carbonate

Chemical Property:

• Appearance/Colour: Colorless and transparent liquid
• Vapor Pressure: 1.979mmHg at 25°C
• Refractive Index: 1.424
• Boiling Point: 164.31 °C at 760 mmHg
• Flash Point: 55.181 °C
• PSA: 35.53000
• Density: 1.114 g/cm^>3
• LogP: 2.13280
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

1-Chloroethyl Isopropyl Carbonate ^*data from reagent suppliers

Safty Information:

• Statements: 10-34
• Safety Statements: 16-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Chloroethyl isopropyl carbonate

There total 4 articles about 1-Chloroethyl isopropyl carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

carbonochloridic acid 1-chloro-ethyl ester (50893-53-3) + isopropyl alcohol (67-63-0,8013-70-5) → 1-(isopropoxycarbonyloxy)ethyl chloride (98298-66-9)

Guidance literature:

With pyridine; at -78 - 25 ℃;

Reference yield: 73.0%

→ 1-(isopropoxycarbonyloxy)ethyl chloride (98298-66-9)

Guidance literature:

With pyridine; In water; at 20 ℃; for 2h; Cooling;

Reference yield:

carbonochloridic acid 1-chloro-ethyl ester (50893-53-3) → 1-(isopropoxycarbonyloxy)ethyl chloride (98298-66-9)

Guidance literature:

upstream raw materials:

carbonochloridic acid 1-chloro-ethyl ester

isopropyl alcohol

phosgene

acetaldehyde

Downstream raw materials:

cefpodoxime proxetil

1-(isopropyloxycarbonyloxy)ethyl trans-4-aminomethylcyclohexanecarboxylate hydrochloride

Refernces

• 1、 -. "Halogenated imidazole compound as well as preparation method and application thereof". Paragraph 0025-0031. . Retrieved 2020/01/25.
• 2、 Reddy, Peketi Rajesh,Musunuri, Sivanadh,Reddy, D. Ramasekhara,Chittala, V. Subrahmanyam,Murthy,Krishnamohan. "Synthesis and characterization of novel analogues of cefpodoxime proxetil". . p. 1751 - 1755. Retrieved 2020/07/30.