Dihydrostreptomycin

Base Information

• Chemical Name: Dihydrostreptomycin
• CAS No.: 128-46-1
• Molecular Formula: C₂₁H₄₁N₇O₁₂
• Molecular Weight: 583.596
• European Community (EC) Number: 204-888-2
• UNII: P2I6R8W6UA
• DSSTox Substance ID: DTXSID0022937
• Nikkaji Number: J10.276H
• Wikipedia: Dihydrostreptomycin
• Wikidata: Q3707637
• NCI Thesaurus Code: C61724
• Metabolomics Workbench ID: 52219
• ChEMBL ID: CHEMBL1950576
• Mol file: 128-46-1.mol

Synonyms:Citrocil;Dihydrostreptomycin;Dihydrostreptomycin Sulfate;Sulfate, Dihydrostreptomycin

Chemical Property of Dihydrostreptomycin

Chemical Property:

• Appearance/Colour: Slightly beige solid.
• Vapor Pressure: 0mmHg at 25°C
• Melting Point: >300 °C
• Refractive Index: 1.762
• Boiling Point: 954.5 °C at 760 mmHg
• PKA: pKa 7.8 (Uncertain)
• Flash Point: 531.1 °C
• PSA: 334.59000
• Density: 1.99 g/cm³
• LogP: -5.17560
• XLogP3: -8.2
• Hydrogen Bond Donor Count: 13
• Hydrogen Bond Acceptor Count: 15
• Rotatable Bond Count: 9
• Exact Mass: 583.28131977
• Heavy Atom Count: 40
• Complexity: 911

Purity/Quality:

99% ^*data from raw suppliers

Dihydrostreptomycin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1C(C(C(O1)OC2C(C(C(C(C2O)O)N=C(N)N)O)N=C(N)N)OC3C(C(C(C(O3)CO)O)O)NC)(CO)O
• Isomeric SMILES: C[C@H]1[C@@]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H]([C@@H]([C@H]2O)O)N=C(N)N)O)N=C(N)N)O[C@H]3[C@H]([C@@H]([C@H]([C@@H](O3)CO)O)O)NC)(CO)O
• Uses: Antibacterial.
• Therapeutic Function: Antibiotic

Technology Process of Dihydrostreptomycin

There total 4 articles about Dihydrostreptomycin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ dihydrostreptomycin (128-46-1,82443-21-8,77093-29-9)

Guidance literature:

With water; nickel; at 75 ℃; under 36775.4 - 51485.6 Torr; Hydrogenation;

Reference yield:

→ dihydrostreptomycin (128-46-1,82443-21-8,77093-29-9)

Guidance literature:

With sodium borate; water; triethylamine;

DOI:10.1021/ja01649a057

Reference yield:

streptomicin (57-92-1) → dihydrostreptomycin (128-46-1,82443-21-8,77093-29-9)

Guidance literature:

With sulfuric acid; water; bei der elektrochemischen Reduktion an einer Cadmium-Amalgam-Kathode;

upstream raw materials:

streptomicin

water

Downstream raw materials:

1,1'-[(1S,3R,4S,6R)-2,4,5,6-tetrahydrocyclohexane-1,3-diyl]diguanidinium sulfate

3-hydroxymethyl-O²-(2-methylamino-2-deoxy-α-L-glucopyranosyl)-5-deoxy-L-lyxose

formaldehyd