3,3-dichloro-1,2-diphenylcyclopropene

Base Information

• Chemical Name: 3,3-dichloro-1,2-diphenylcyclopropene
• CAS No.: 2570-00-5
• Molecular Formula: C₁₅H₁₀Cl₂
• Molecular Weight: 261.15
• Mol file: 2570-00-5.mol

Synonyms:3,3-dichloro-1,2-diphenylcyclopropene

Chemical Property of 3,3-dichloro-1,2-diphenylcyclopropene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,3-dichloro-1,2-diphenylcyclopropene

There total 7 articles about 3,3-dichloro-1,2-diphenylcyclopropene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

diphenylcyclopropenone (886-38-4) → 3,3-dichloro-1,2-diphenylcyclopropene (2570-00-5)

Guidance literature:

With thionyl chloride; at 40 ℃; for 2h; Inert atmosphere;

DOI:10.1039/c1dt10109a

Reference yield: 87.0%

2,3-diphenylcyclopropenone (52730-95-7) → 3,3-dichloro-1,2-diphenylcyclopropene (2570-00-5)

Guidance literature:

With thionyl chloride; at 50 ℃; for 2h; Inert atmosphere; Neat (no solvent);

DOI:10.1021/ol102980t

Reference yield:

benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → 3,3-dichloro-1,2-diphenylcyclopropene (2570-00-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: aluminum (III) chloride / dichloromethane / 4 h / -78 - 20 °C / Inert atmosphere; Sealed tube

1.2: Inert atmosphere; Sealed tube

2.1: thionyl chloride / dichloromethane / 2 h / 50 °C / Inert atmosphere; Sealed tube

With aluminum (III) chloride; thionyl chloride; In dichloromethane;

DOI:10.1021/acs.orglett.9b04656

upstream raw materials:

diphenylcyclopropenone

2,3-diphenylcyclopropenone

benzene

phenylacetic acid

Downstream raw materials:

C₃₉H₃₀O₂P₂

(η5-MeCp)(carbonyl)2Mn(1,2-diphenylcyclopropenylidene)

chlorotriphenylgermane

(Ph₃P)(carbonyl)3Fe(1,2-diphenylcyclopropenylidene)

Refernces

• 1、 Nanda, Tanmayee,Ravikumar, P. C.. "A Palladium-Catalyzed Cascade C-C Activation of Cyclopropenone and Carbonylative Amination: Easy Access to Highly Functionalized Maleimide Derivatives". supporting information. . Retrieved 2020/02/15.
• 2、 Vathsala,Srinivasulu,Santhosh,Sureshbabu, Vommina V.. "The synthesis of Nα-protected amino hydroxamic acids from Nα-protected amino acids employing versatile chlorinating agent CPI-Cl". . p. 449 - 457. Retrieved 2019/03/08.