4,5-Diamino-1-(2-hydroxyethyl)pyrazole sulfate

Base Information

• Chemical Name: 4,5-Diamino-1-(2-hydroxyethyl)pyrazole sulfate
• CAS No.: 155601-30-2
• Molecular Formula: C5H10N4O^.H2SO4
• Molecular Weight: 240.24
• Hs Code.: 2933199090
• Mol file: 155601-30-2.mol

Synonyms:4,5-diamino-1-hyoxyethyl pyrazole sulfate;4,5-Diamino-1-(2-Hydroxyethyl) Pyrazole Suflate;4,5-Diamino-1-(2-hydroxyethyl)pyrazole sulphate;1-hydroxyethyl 4,5-diamino pyrazole sulfate;

Chemical Property of 4,5-Diamino-1-(2-hydroxyethyl)pyrazole sulfate

Chemical Property:

• Appearance/Colour: Off-white to pink powder
• Vapor Pressure: 2.29E-07mmHg at 25°C
• Melting Point: >183 °C
• Boiling Point: 407.4 °C at 760 mmHg
• Flash Point: 200.2 °C
• PSA: 173.07000
• Density: 1.69-1.87 at 20℃
• LogP: 0.63020
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

4,5-Diamino-1-(2-hydroxyethyl)pyrazoleSulfate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi,N
• Hazard Codes: Xi,N
• Statements: 41-43-51/53
• Safety Statements: 24-26-37/39-61

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 4,5-Diamino-1-(2-hydroxyethyl)pyrazole Sulfate is useful as an oxidative hair dye.

Technology Process of 4,5-Diamino-1-(2-hydroxyethyl)pyrazole sulfate

There total 4 articles about 4,5-Diamino-1-(2-hydroxyethyl)pyrazole sulfate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.7%

5-amino-1-(2'-hydroxyethyl)-4-phenylazopyrazole hydrochloride (924897-89-2) → 4,5-diamino-1-(2-hydroxyethyl)pyrazole sulfate (155601-30-2)

Guidance literature:

5-amino-1-(2'-hydroxyethyl)-4-phenylazopyrazole hydrochloride; With hydrogen; 1.0% Pd/C; In methanol; at 60 ℃; under 10763.6 Torr;

With sulfuric acid; In methanol; at 30 ℃;

Reference yield:

5-amino-1-(2-hydroxyethyl)-4-nitrosopyrazole (128564-63-6) → 4,5-diamino-1-(2-hydroxyethyl)pyrazole sulfate (155601-30-2)

Guidance literature:

With sulfuric acid; hydrogen; palladium 10% on activated carbon; In water; at 20 ℃; for 96h;

Reference yield:

2-hydroxyethylhydrazine (109-84-2) + diethyl 2-ethoxymethylenemalonate (87-13-8) → 4,5-diamino-1-(2-hydroxyethyl)pyrazole sulfate (155601-30-2)

Guidance literature:

2-hydroxyethylhydrazine; diethyl 2-ethoxymethylenemalonate; In ethanol; water; at 45 - 80 ℃; under 2250.23 - 3000.3 Torr; Large scale;

With water; sodium hydroxide; Further stages; Large scale;

upstream raw materials:

5-amino-1-(2-hydroxyethyl)-4-nitrosopyrazole

5-amino-1-(2'-hydroxyethyl)-4-phenylazopyrazole hydrochloride

2-hydroxyethylhydrazine

diethyl 2-ethoxymethylenemalonate

Downstream raw materials:

4-[5-amino-1-(2-hydroxyethyl)-1H-pyrazol-4-ylimino]-3-hydroxy-2-methyl-cyclohexa-2,5-dienone

2-[5-amino-1-(2-hydroxyethyl)-1H-pyrazol-4-ylamino]-5-(2-hydroxyethyl-amino)[1,4]benzoquinone

2-[5-amino-1-(2-hydroxyethyl)-1H-pyrazol-4-ylamino]-4-[5-amino-1-(2-hydroxy-ethyl)-1H-pyrazol-4-ylimino]-5-hydroxycyclo-hexa-2,5-dienone

3-amino-4-[5-amino-1-(2-hydroxy-ethyl)-1H-pyrazol-4-ylimino]-2-chloro-6-methylcyclohexa-2,5-dienone

Refernces

• 1、 -. "Preparation of 4,5-diamino-1-(substituted)-pyrazole and acid addition salts thereof". Page/Page column 5. . Retrieved 2010/11/25.
• 2、 -. "Preparation of 4,5-diamino-1-(2'-hydroxyethyl)-pyradazole and acid addition salts thereof". . . Retrieved 2008/06/13.