4-Nitro-1,3-phenylenediamine sulfate

Base Information

• Chemical Name: 4-Nitro-1,3-phenylenediamine sulfate
• CAS No.: 200295-57-4
• Molecular Formula: C6H7N3O2^.H2SO4
• Molecular Weight: 251.22
• Mol file: 200295-57-4.mol

Synonyms:4-Nitro-1,3-benzenediamine sulfate (1:1);p-Nitro-m-phenylenediamine sulfate;

Chemical Property of 4-Nitro-1,3-phenylenediamine sulfate

Chemical Property:

• Boiling Point: 648.6 °C at 760 mmHg
• Flash Point: 346 °C
• PSA: 180.84000
• LogP: 2.87280
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

4-Nitrobenzene-1,3-diamine sulfate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Nitro-1,3-phenylenediamine sulfate

There total 8 articles about 4-Nitro-1,3-phenylenediamine sulfate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-amino-5-chlorobenzyl alcohol (37585-25-4) → 2-amino-5-chlorobenzaldehyde (20028-53-9)

Guidance literature:

With manganese(IV) oxide; In diethyl ether; at 20 ℃;

Reference yield: 95.0%

→ p-nitro-m-phenylenediamine sulfate (200295-57-4)

Guidance literature:

Reference yield: 70.0%

5-chloro-2-nitrobenzaldehyde (6628-86-0) → 2-amino-5-chlorobenzaldehyde (20028-53-9)

Guidance literature:

With hydrogenchloride; iron; In ethanol; water; acetic acid; at 20 ℃; for 0.916667h; Reflux;

DOI:10.1021/ol102376a

upstream raw materials:

5-chloro-2-nitrobenzaldehyde

4-chloro-aniline

N,N-dimethyl-formamide

2-amino-5-chlorobenzyl alcohol

Refernces

• 1、 Meng, Xiang-He,Wu, Dan-Ni,Zhang, Yu-Jia,Zhao, Yu-Long. "PPTS-Catalyzed Bicyclization Reaction of 2-Isocyanobenzaldehydes with Various Amines: Synthesis of Diverse Fused Quinazolines". supporting information. p. 1923 - 1929. Retrieved 2021/02/26.
• 2、 Laraia, Luca,Olsen, Asger Hegelund,Whitmarsh-Everiss, Thomas. "Identification of Inhibitors of Cholesterol Transport Proteins Through the Synthesis of a Diverse, Sterol-Inspired Compound Collection". supporting information. p. 26755 - 26761. Retrieved 2021/11/17.