Azodicarbonamide

Base Information

• Chemical Name: Azodicarbonamide
• CAS No.: 123-77-3
• Deprecated CAS: 52737-71-0,62494-61-5,62494-62-6,62494-85-3,65098-86-4,65098-87-5,72514-45-5,73247-42-4,73905-77-8,81774-20-1,89073-35-8,97707-96-5,183256-78-2,218433-14-8,221272-72-6,1006730-14-8,131715-26-9,882523-85-5,1242528-98-8,1394903-25-3,882507-89-3,1349861-61-5,2250070-22-3,885108-45-2
• Molecular Formula: C2H4N4O2
• Molecular Weight: 116.079
• Hs Code.: 29270000
• European Community (EC) Number: 204-650-8
• ICSC Number: 0380
• NSC Number: 674447,41038
• UN Number: 3242
• UNII: 56Z28B9C8O
• Wikipedia: Azodicarbonamide
• Pharos Ligand ID: G48P9UFNT725
• Metabolomics Workbench ID: 43939
• ChEMBL ID: CHEMBL28517
• Mol file: 123-77-3.mol

Synonyms:1,1'-azobis(formamide);1,1'-azobisformamide;azobiscarboxamide;azodicarbonamide

Chemical Property of Azodicarbonamide

Chemical Property:

• Appearance/Colour: orange crystalline powder
• Vapor Pressure: 0Pa at 25℃
• Melting Point: 220-225 ºC (dec.)
• Refractive Index: 1.762
• Boiling Point: 284.8 ºC at 760mmHg
• PKA: 14.45±0.50(Predicted)
• Flash Point: 126 ºC
• PSA: 110.90000
• Density: 1.87 g/cm³
• LogP: 0.99660
• Storage Temp.: Flammables area
• Solubility.: water: soluble0.033g/L at 20°C
• Water Solubility.: SOLUBLE IN HOT WATER
• XLogP3: -1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 116.03342538
• Heavy Atom Count: 8
• Complexity: 123
• Transport DOT Label: Flammable Solid

Purity/Quality:

99% ^*data from raw suppliers

Azodicarboxamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 42-44-R44-R42
• Safety Statements: 22-24-37-S37-S24-S22

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Nitrogen Compounds -> Other Nitrogen Compounds
• Canonical SMILES: C(=O)(N)N=NC(=O)N
• Isomeric SMILES: C(=O)(N)/N=N/C(=O)N
• Recent EU Clinical Trials: Estudio piloto, doble ciego, aleatorizado, controlado con placebo, de dosis repetida, para la evaluación de la seguridad y la eficacia antiviral de HPH116 en pacientes infectados por VIH-1 que no hayan recibido tratamiento previo
• Inhalation Risk: Evaporation at 20 °C is negligible; a harmful concentration of airborne particles can, however, be reached quickly.
• Effects of Short Term Exposure: The substance is irritating to the eyes and respiratory tract. Inhalation of dust may cause asthmatic reactions.
• Effects of Long Term Exposure: Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged contact may cause skin sensitization. Repeated or prolonged inhalation may cause asthma.
• Description: Azodicarbonamide is a synthetic chemical that exists at ambient temperature as a yellow-orange crystalline solid. Azodicarbonamide is mainly used as a blowing agent in the rubber and plastics industries in the expansion of a wide range of polymers, including polyvinyl chloride, polyolefins, and natural/synthetic rubbers. Azodicarbonamide is also used as a food additive, such as an aging and bleaching ingredient in cereal flour and as a dough conditioner in bread baking.
• Uses: Azodicarboxamide is used as an additive to wheat flour breads and dough to improve the physical properties of the dough and the baking performance. It is also used to optimize the levels of oxidant/re ducing agents in the baking of wheat flour. As blowing and foaming agent for plastics; as maturing and bleaching agent in cereal flour. Azodicarbonamide is a dough conditioner that exists as a yellow to orange-red crystalline powder practically insoluble in water. it is used in aging and bleaching cereal flour to produce a more manage- able dough and a lighter, more voluminous loaf of bread. it is used in bread flours and bread as a dough conditioner. it can be used with the oxidizing agent potassium bromate. a typical use level is less than 45 ppm.

Technology Process of Azodicarbonamide

There total 16 articles about Azodicarbonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.9%

urea (57-13-6) → Azodicarboxamid (123-77-3,97707-96-5)

Guidance literature:

With sodium bromide; In water; for 2.7h; Reagent/catalyst; Temperature; Cooling with ice; Electrolysis; Green chemistry;

Reference yield: 99.0%

hydrazodicarboxamide (110-21-4) → Azodicarboxamid (123-77-3,97707-96-5)

Guidance literature:

With acetic acid; copper(I) bromide; at 20 ℃; for 12h; under 760.051 Torr; Reagent/catalyst; Temperature; Sealed tube;

Reference yield: 96.0%

sodium chlorobiuret salt + sodium chlorobiuret salt → Azodicarboxamid (123-77-3,97707-96-5)

Guidance literature:

With ammonia; phosphorus tribromide; In water; at 10 - 60 ℃; for 21915h; Product distribution / selectivity;

upstream raw materials:

hydrazodicarboxamide

diethylazodicarboxylate

monofluorourea

carbamoyl azide

Downstream raw materials:

5-(3-nitro-phenyl)-1,2-dihydro-[1,2,4]triazol-3-one

hydrazodicarboxamide

C₁₂H₁₉N₄O₂P

C₁₅H₁₇N₄O₂P

Refernces

• 1、 -. "METHOD FOR PRODUCING AZO COMPOUNDS". Paragraph 0048; 0049; 0050; 0051; 0052; 0053-0058. . Retrieved 2018/05/03.
• 2、 -. "METHOD FOR PRODUCING AZO COMPOUNDS". Paragraph 0044; 0046-0049. . Retrieved 2018/08/22.