Sodium Chloride

Base Information

• Chemical Name: Sodium Chloride
• CAS No.: 7647-14-5
• Deprecated CAS: 11062-32-1,11062-43-4,8028-77-1,418758-90-4,11062-43-4,418758-90-4
• Molecular Formula: NaCl
• Molecular Weight: 58.4428
• Hs Code.: 38220000
• European Community (EC) Number: 231-598-3,617-042-6
• NSC Number: 77364
• UNII: 451W47IQ8X
• DSSTox Substance ID: DTXSID3021271
• Nikkaji Number: J44.029I
• Wikipedia: Sodium chloride,Sodium_chloride
• Wikidata: Q2314
• NCI Thesaurus Code: C29974,C822
• RXCUI: 9863
• ChEMBL ID: CHEMBL1200574
• Mol file: 7647-14-5.mol

Synonyms:Sodium Chloride;Sodium Chloride, (22)Na;Sodium Chloride, (24)NaCl

Chemical Property of Sodium Chloride

Chemical Property:

• Appearance/Colour: Colorless crystals
• Vapor Pressure: 1 mm Hg ( 865 °C)
• Melting Point: 801 °C, 1074 K, 1474 °F
• Refractive Index: n20/D 1.378
• Boiling Point: 1413 °C, 1686 K, 2575 °F
• Flash Point: 1413°C
• PSA: 0.00000
• Density: 2.165 g/cm³
• LogP: -2.99600
• Storage Temp.: 2-8°C
• Sensitive.: Hygroscopic
• Solubility.: H2O: soluble
• Water Solubility.: 360 g/L (20 ºC)
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 57.9586220
• Heavy Atom Count: 2
• Complexity: 2

Purity/Quality:

97% ^*data from raw suppliers

Sodium chloride ≥98% (titration) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36-36/37/38-22
• Safety Statements: 24/25-26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Metals -> Metals, Inorganic Compounds
• Canonical SMILES: [Na+].[Cl-]
• Recent ClinicalTrials: Terlipressin Infusion During Whipple Procedure: Effect on Blood Loss and Transfusion Needs
• Recent EU Clinical Trials: ECOGUIDED GENICULAR NERVE BLOCK IN PATIENTS WITH KNEE OSTEOARTHRITIS BY LOCAL ANESTHETIC OR BY COMBINATION OF LOCAL ANESTHETIC AND CORTICOID: PLACEBO-CONTROLLED RANDOMIZED BLIND CLINICAL TRIAL
• Recent NIPH Clinical Trials: Single Ascending-dose Study of Injectable Favipiravir
• Traditional Use in Curing Processes: Sodium chloride has been traditionally employed in curing processes for meat products. It serves as a preservative and modifies the water-holding capacity of proteins. In meat products, NaCl plays a crucial role in extracting myofibrillar proteins, contributing to meat particle binding, fat emulsification, and water-holding capacity, thereby reducing cook losses and enhancing quality and texture.
• Effects on Ornamental Shrubs: Sodium chloride can impact ornamental shrubs in various ways, including reduced growth, inhibition of root growth, leaf damage, and interference with nutrient uptake. Maintaining a high K+/Na+ ratio in plant tissues is essential for salt tolerance. However, the competitive effect of Na+ concentration in the rhizosphere on K+ uptake can affect this ratio, influencing the salt tolerance of ornamental shrubs. Some shrubs exhibit tolerance mechanisms by limiting the uptake and transport of Na+ and Cl鈭? to aerial parts, retaining these ions in roots and lower stems.
• Association with Autoimmune Diseases: Sodium chloride has been implicated in driving autoimmune diseases by inducing pathogenic TH17 cells. High-salt conditions have been shown to enhance the induction of TH17 cells by activating specific signaling pathways. Inhibition of these pathways prevents the development of TH17 cells under high-salt conditions.
• Relationship with Hypertension and Dietary Trends: While there is a well-established relationship between high sodium intake and hypertension, recent studies have shown that this relationship may not apply to the entire population. Nevertheless, there is a tendency to reduce the amount of NaCl in foods. NaCl contributes to various properties of meat products, including water-holding capacity, fat binding, color, flavor, and texture. Research has explored replacing a portion of NaCl with chloride salt mixtures in dry fermented sausage, resulting in acceptable texture and color properties while avoiding negative effects associated with excessive concentration.

Technology Process of Sodium Chloride

There total 718 articles about Sodium Chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

sodium azide + nitrosylchloride (2696-92-6) → nitrogen (7727-37-9) + sodium chloride (7647-14-5) + dinitrogen monoxide (10024-97-2)

Guidance literature:

In diethyl ether; below 0°C;;

Reference yield:

sodium bromide (7647-15-6) → hydrogen bromide (10035-10-6,12258-64-9) + sodium chloride (7647-14-5)

Guidance literature:

With hydrogenchloride; In melt; equil.; ground body at 850-950°C NaBr-NaCl melt;;

Reference yield:

hydrogenchloride (7647-01-0,15364-23-5) + sodium bromide (7647-15-6) → hydrogen bromide (10035-10-6,12258-64-9) + sodium chloride (7647-14-5)

Guidance literature:

In neat (no solvent); at 800°C;;

upstream raw materials:

hydrogenchloride

sodium chlorite

trichloroisocyanuric acid

aminosulfonic acid

Downstream raw materials:

6-[(4,6-diphenyl-2-pyridinyl)oxy]-2,2-dimethyl-1-hexylamine

sodium nitrate

sodium carbonate

sodium hydrogencarbonate

Refernces

• 1、 Finholt, A. E.,Barbaras, G. D.,Barbaras, G. K.,Urry, G.,Wartik, T.,Schlesinger, H. I.. "". . p. 317 - 325. Retrieved 1955.
• 2、 Jaro, Tomasz,Orlowski, Piotr A.,Wegner, Wojciech,Fijalkowski, Karol J.,Leszczyski, Piotr J.,Grochala, Wojciech. "Hydrogen storage materials: Room-temperature wet-chemistry approach toward mixed-metal borohydrides". . p. 1236 - 1239. Retrieved 2015.
• 3、 Weiss, P. S.,Mestdagh, J. M.,Covinsky, M. H.,Balko, B. A.,Lee, Y. T.. "". . p. 93 - 110. Retrieved 1988.
• 4、 Patrick, P. F.,McCallum, K. J.. "". . p. 766 - 767. Retrieved 1962.
• 5、 Boccalon,Nocchetti,Pica,Romani,Casciola. "Layered double hydroxide and zirconium phosphate as ion exchangers for the removal of 'black crusts' from the surface of ancient monuments". . p. 2976 - 2985. Retrieved 2018.
• 6、 Weiss, P. S.,Mestdagh, J. M.,Schmidt, H.,Covinsky, M. H.,Lee, Y. T.. "Reactions of Ground-State and Electronically Excited Sodium Atoms with Methyl Bromide and Molecular Chlorine". . p. 3005 - 3011. Retrieved 1991.
• 7、 Ren, Changxu,Yang, Peng,Gao, Jinyu,Huo, Xiangchen,Min, Xiaopeng,Bi, Eric Y.,Liu, Yiming,Wang, Yin,Zhu, Mengqiang,Liu, Jinyong. "Catalytic Reduction of Aqueous Chlorate with MoO xImmobilized on Pd/C". . p. 8201 - 8211. Retrieved 2020.
• 8、 Bauer, Susan K.,Willis, Christopher J.,Payne, Nicholas C.. "Diiodobis(isopropyldiphenylphosphine oxide-O)cobalt(II)". . p. 586 - 588. Retrieved 1995.
• 9、 Schneider,Politi,Baptista. "Development of a heat-sensor for the measurement of reaction enthalpy based on laser deflection". . p. 179 - 184. Retrieved 2000.
• 10、 Baranwal, Balram P.,Fatma, Talat,Singh, Alok K.,Varma, Anand. "Nano-sized titanium(IV) ternary and quaternary complexes with electron-rich oxygen-based bidentate ligands". . p. 3461 - 3464. Retrieved 2009.