N-Acetyl-D-leucine

Base Information Edit

Chemical Name:N-Acetyl-D-leucine
CAS No.:19764-30-8
Molecular Formula:C8H15NO3
Molecular Weight:173.212
Hs Code.:29241900
UNII:91WU82GA22
DSSTox Substance ID:DTXSID50361310
Nikkaji Number:J21.921E
Wikidata:Q72435344
ChEMBL ID:CHEMBL174357
Mol file:19764-30-8.mol

Synonyms:N-Acetyl-D-leucine;19764-30-8;Ac-D-Leu-OH;D-leucine, N-acetyl-;N-Acetyl-R-leucine;(2R)-2-acetamido-4-methylpentanoic acid;Acetylleucine, D-;Acetylleucine, (R)-;(R)-2-acetamido-4-methylpentanoic acid;Leucine, N-acetyl-, D-;UNII-91WU82GA22;acetyl-d-leucine;91WU82GA22;MFCD00066069;2,N-Acetyl-D-leucine;D-acetylleucine;(R)-acetylleucine;N-acetyl-D-Leu;NCGC00094935-01;N-acetyl-(D)-leucine;SCHEMBL714003;CHEMBL174357;CHEBI:94479;DTXSID50361310;CHEBI:146296;HY-Y1080;s4514;AKOS016842336;AKOS025117328;CCG-266380;CS-W020713;DS-1211;FD21901;NCGC00094935-02;AC-22376;A0713;AM20090137;A-1455;A20910;EN300-321381;Q-100200;BRD-K05831461-001-01-8;Z851793110

Suppliers and Price of N-Acetyl-D-leucine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Acetyl-D-leucine
100mg
$ 70.00

TCI Chemical
N-Acetyl-D-leucine >99.0%(T)
1g
$ 184.00

Sigma-Aldrich
N-Acetyl-D-leucine
5g
$ 320.00

Matrix Scientific
N-Acetyl-D-leucine 95+%
100g
$ 102.00

Matrix Scientific
N-Acetyl-D-leucine 95+%
5g
$ 10.00

Matrix Scientific
N-Acetyl-D-leucine 95+%
25g
$ 37.00

Iris Biotech GmbH
Ac-D-Leu-OH
1 g
$ 67.50

Iris Biotech GmbH
Ac-D-Leu-OH
5 g
$ 236.25

Crysdot
Ac-D-Leu-OH 95+%
500g
$ 414.00

Chem-Impex
Acetyl-D-leucine,≥99%(Assaybytitration) ≥99%(Assaybytitration)
250G
$ 477.57

Total 126 raw suppliers

Chemical Property of N-Acetyl-D-leucine Edit

Chemical Property:

Melting Point:176-177 °C
Refractive Index:23 ° (C=4, EtOH)
Boiling Point:369.7 °C at 760 mmHg
PKA:3.67±0.10(Predicted)
Flash Point:177.4 °C
PSA：66.40000
Density:1.069 g/cm³
LogP:1.01270
Storage Temp.:−20°C
Solubility.:DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly)
XLogP3:0.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:173.10519334
Heavy Atom Count:12
Complexity:177

Purity/Quality:

99.0% ^*data from raw suppliers

N-Acetyl-D-leucine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC(C(=O)O)NC(=O)C
Isomeric SMILES:CC(C)C[C@H](C(=O)O)NC(=O)C

Technology Process of N-Acetyl-D-leucine

There total 7 articles about N-Acetyl-D-leucine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 328-38-1,21675-61-6,25248-98-0,70-45-1
(R)-leucine

: 830-03-5
4-nitrophenol acetate

: 100-02-7,78813-13-5,89830-32-0
4-nitro-phenol

: 19764-30-8
N-acetyl-D-leucine

Guidance literature:: β‐cyclodextrin; In water; dimethyl sulfoxide; at 25 ℃; Rate constant; Mechanism; various conditions;

Reference yield:

: 99-15-0
N-acetylleucine

: 61-90-5,21675-61-6,25248-98-0,70-45-1
L-leucine

: 19764-30-8
N-acetyl-D-leucine

Guidance literature:: With potassium hydroxide; potassium phosphate buffer; porcine kidney acylase I; at 40 ℃; relative initial rate of hydrolysis;
DOI:10.1021/ja00198a055

Reference yield:

: 64896-30-6
(Z)-2-Acetylamino-4-methyl-pent-2-enoic acid

: 1188-21-2
N-Ac-Leu

: 19764-30-8
N-acetyl-D-leucine

Guidance literature:: With <(1R;2R-MAC-PONP)Rh(COD)>(+)BF4(-); hydrogen; In methanol; at 30 ℃; under 750.06 Torr; Title compound not separated from byproducts;