Sodium lauroylsarcosinate

Base Information

• Chemical Name: Sodium lauroylsarcosinate
• CAS No.: 137-16-6
• Molecular Formula: C15H28NNaO3
• Molecular Weight: 293.382
• Hs Code.: 3402.11 DERIVATION
• Mol file: 137-16-6.mol

Synonyms:Glycine,N-methyl-N-(1-oxododecyl)-, sodium salt (1:1);Glycine,N-methyl-N-(1-oxododecyl)-, sodium salt (9CI);Sarcosine, N-lauroyl-, sodiumsalt (8CI);N-Dodecanoyl-N-methylglycine sodium salt;N-Dodecanoylsarcosine sodium salt;N-Lauroyl-N-methylglycine sodium salt;N-Lauroylsarcosine sodium;Nikkol SarcosinateLN;Nikkol Sarcosinate LN 3;Nikkol Sarcosine Na;Oramix L 30;Perlastan L 30;ProtelanLS 9011;

Chemical Property of Sodium lauroylsarcosinate

Chemical Property:

• Appearance/Colour: white powder
• Vapor Pressure: 0.02 hPa (20 °C)
• Melting Point: 46 °C
• Boiling Point: 413.2 °C at 760 mmHg
• Flash Point: 203.7 °C
• PSA: 60.44000
• Density: 1.033 g/mL at 20 °C
• LogP: 2.11560
• Storage Temp.: room temp
• Sensitive.: Hygroscopic
• Solubility.: H2O: 1 M at 20 °C, clear, colorless
• Water Solubility.: Soluble in water (293 g/L).

Purity/Quality:

99% ^*data from raw suppliers

LauroylsarcosineSodiumSalt ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,T
• Statements: 36/37/38-41-38-23
• Safety Statements: 22-24/25-36/37/39-27-26-45-38-37/39

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Sodium lauroyl sarcosinate (INCI), also known as sarkosyl, is a white powder derived from sarcosine, which make it is fate-free and biodegradable. The surfactant is amphiphilic due to the hydrophobic 12-carbon chain (lauroyl) and the hydrophilic carboxylate. Sodium lauroyl sarcosinate is personal care products as well as in household and industrial applications, and it is used as a co-surfactant in cleanser formulations such as shampoos and body washes. It can also be used in oral care applications such as toothpastes and incorporated into syndet and combo bars. The typical usage levels range from 1-5% on an active basis. Detergent, foaming agent, antienzyme for dentifrices: King, US 2689170 (1954 to Colgate-Palmolive). N-Lauroylsarcosine is used for solubilization and separation of membrane proteins and glycoprotein's; reported to inhibit hexokinase. It is useful in concentrated salt solutions used in the cell lysis step during RNA purification (helps avoid excessive foaming). It has been used to indicate paramagnetic anisotropy sign change in micelle mesophage. Inhibits bacterial flora of human saliva/gut at 0.25% as well as acting as a fungi static agent in aqueous dispersion (1%). Suitable forsolubilization and separation of membrane proteinslysis of cells during the isolation of RNA inhibition of hexokinase

Technology Process of Sodium lauroylsarcosinate

There total 5 articles about Sodium lauroylsarcosinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

N-acyl sarcosinate (97-78-9) → sodium N-lauroylsarcosinate (137-16-6)

Guidance literature:

With sodium hydroxide; In ethanol; at 50 - 70 ℃;

Reference yield: 97.0%

n-dodecanoyl chloride (112-16-3) + sarcosine (107-97-1,25951-24-0) → sodium N-lauroylsarcosinate (137-16-6)

Guidance literature:

With sodium hydroxide; In water; at 15 - 20 ℃; pH=8 - 10;

Reference yield:

n-dodecanoyl chloride (112-16-3) + sodium sarcosinate (4316-73-8) → sodium N-lauroylsarcosinate (137-16-6)

Guidance literature:

In water; at 10 - 30 ℃; for 5h; pH=10.3 - 10.6; Inert atmosphere;

upstream raw materials:

n-dodecanoyl chloride

sodium sarcosinate

lauric acid

sarcosine

Refernces

• 1、 -. "Method used for synthesizing lauroyl amino acid sodium based on polyethylene glycol phase transfer catalyst". Paragraph 0034; 0035. . Retrieved 2017/03/14.
• 2、 -. "Method to Produce N-Acyl Amino Acid Surfactants Using N-Acyl Amino Acid Surfactants or the Corresponding Anhydrides as Catalysts". Paragraph 0075. . Retrieved 2015/05/26.