3,5-Dimethylbenzyl bromide

Base Information

• Chemical Name: 3,5-Dimethylbenzyl bromide
• CAS No.: 27129-86-8
• Molecular Formula: C9H11Br
• Molecular Weight: 199.09
• Hs Code.: 29036990
• Mol file: 27129-86-8.mol

Synonyms:alpha-Bromomesitylene;1-(bromomethyl)-3,5-dimethyl-benzene;a-Bromomesitylene;3,5-DIMETHYL BENZYL BROMIDE;1-(bromomethyl)-3,5-dimethylbenzene;3,5-Dimethylbenzylbromide;

Chemical Property of 3,5-Dimethylbenzyl bromide

Chemical Property:

• Appearance/Colour: white to light yellow crystal powde
• Vapor Pressure: 0.0934mmHg at 25°C
• Melting Point: 36-40 ºC
• Refractive Index: 1.554
• Boiling Point: 101-103 ºC (8 mmHg)
• Flash Point: 99 °C
• PSA: 0.00000
• Density: 1.314 g/cm³
• LogP: 3.19830
• Storage Temp.: Store below +30°C.

Purity/Quality:

99% ^*data from raw suppliers

3,5-Dimethylbenzyl bromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34
• Safety Statements: 45-36/37/39-26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,5-Dimethylbenzyl bromide

There total 10 articles about 3,5-Dimethylbenzyl bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3,5-dimethylbenzyl alcohol (27129-87-9) → 1-bromomethyl-3,5-dimethylbenzene (27129-86-8)

Guidance literature:

With phosphorus tribromide; In dichloromethane; at 0 - 20 ℃; for 2h; Inert atmosphere;

DOI:10.1002/chem.201404139

Reference yield: 87.0%

1,3,5-trimethyl-benzene (108-67-8) → 1-bromomethyl-3,5-dimethylbenzene (27129-86-8)

Guidance literature:

With bromine; at 140 ℃;

DOI:10.1016/S0022-328X(01)00725-2

Reference yield: 50.0%

1,3,5-trimethyl-benzene (108-67-8) → 1-bromomethyl-3,5-dimethylbenzene (27129-86-8) + 2,4,6-trimethylphenyl bromide (576-83-0)

Guidance literature:

With sodium bromate; sodium hydrogensulfite; In cyclohexane; water; at 50 ℃; for 4h;

DOI:10.1021/jo972263q

upstream raw materials:

tetrachloromethane

N-Bromosuccinimide

1,3,5-trimethyl-benzene

dibenzoyl peroxide

Downstream raw materials:

diethyl (3,5-dimethylphenylmethyl)malonate

1,3,5-trimethyl-2-(3',5'-dimethylbenzyl)benzene

3,3',5-Trimethyl-diphenylmethan

(3,5-dimethyl-phenyl)-(4-methyl-phenyl)-methane

Refernces

• 1、 Ni, Shengjun,El Remaily, Mahmoud Abd El Aleem Ali Ali,Franzén, Johan. "Carbocation Catalyzed Bromination of Alkyl Arenes, a Chemoselective sp3 vs. sp2 C?H functionalization.". supporting information. p. 4197 - 4204. Retrieved 2018/09/25.
• 2、 Michelet, Bastien,Bour, Christophe,Gandon, Vincent. "Gallium-assisted transfer hydrogenation of alkenes". supporting information. p. 14488 - 14492. Retrieved 2015/04/16.