N-Benzoyl-DL-tyrosil-N',N'-dipropylamide

Base Information

• Chemical Name: N-Benzoyl-DL-tyrosil-N',N'-dipropylamide
• CAS No.: 57227-09-5
• Molecular Formula: C22H28 N2 O3
• Molecular Weight: 368.476
• Hs Code.: 2924299090
• Mol file: 57227-09-5.mol

Synonyms:Benzenepropanamide,a-(benzoylamino)-4-hydroxy-N,N-dipropyl-,(?à)-;CR 1936;

Chemical Property of N-Benzoyl-DL-tyrosil-N',N'-dipropylamide

Chemical Property:

• Boiling Point: 619.102 ºC at 760 mmHg
• PKA: 9.87±0.15(Predicted)
• Flash Point: 328.221 ºC
• PSA: 69.64000
• Density: 1.131 g/cm³
• LogP: 3.77280
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

N-Benzoyl-DL-tyrosyl-N’,N’-dipropylamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: N-Benzoyl-DL-tyrosyl-N',N'-dipropylamide is a metabolite of the antispasmodic agent Tiropramide (T446900). Tiropramide impurity C.

Technology Process of N-Benzoyl-DL-tyrosil-N',N'-dipropylamide

There total 4 articles about N-Benzoyl-DL-tyrosil-N',N'-dipropylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

→ N-benzoyl-DL-tyrosil-di-n-propylamide (57227-09-5)

Guidance literature:

Reference yield:

O.N-Dibenzoyl-DL-tyrosyl-di-n-propylamid (57227-08-4) → N-benzoyl-DL-tyrosil-di-n-propylamide (57227-09-5)

Guidance literature:

With sodium hydroxide;

Reference yield:

N-benzoyl-O-benzoyl-L-tyrosine (14325-35-0) → N-benzoyl-DL-tyrosil-di-n-propylamide (57227-09-5)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) Et₃N, ClCO₂Et, (ii) /BRN= 505974/

2: sodium hydroxide

With sodium hydroxide;

upstream raw materials:

O_.N-Dibenzoyl-DL-tyrosyl-di-n-propylamid

N-benzoyl-O-benzoyl-L-tyrosine

L-tyrosine

Downstream raw materials:

Alfospas

Refernces