2-Methylpropane-2-sulfinamide

Base Information Edit

Chemical Name:2-Methylpropane-2-sulfinamide
CAS No.:196929-78-9
Molecular Formula:C4H11NOS
Molecular Weight:121.203
Hs Code.:29309090
European Community (EC) Number:926-811-8,619-964-4
UNII:42F4K704G0,I85YC2ZA8O,7FEC1T720F
DSSTox Substance ID:DTXSID20391967,DTXSID90463241
Nikkaji Number:J796.219C
Wikipedia:Tert-Butanesulfinamide
Wikidata:Q7705231
Mol file:196929-78-9.mol

Synonyms:tert-butanesulfinamide

Suppliers and Price of 2-Methylpropane-2-sulfinamide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-tert-Butylsulfinamide
1g
$ 65.00

TCI Chemical
(R)-(+)-tert-Butylsulfinamide >98.0%(GC)
1g
$ 58.00

TCI Chemical
(R)-(+)-tert-Butylsulfinamide >98.0%(GC)
5g
$ 174.00

Strem Chemicals
(R)-(+)-t-Butylsulfinamide, min. 97%
5g
$ 381.00

Strem Chemicals
(R)-(+)-t-Butylsulfinamide, min. 97%
25g
$ 865.00

Strem Chemicals
(R)-(+)-t-Butylsulfinamide, min. 97%
1g
$ 95.00

Sigma-Aldrich
(R)-(+)-2-Methyl-2-propanesulfinamide 98%
1g
$ 70.40

Sigma-Aldrich
(R)-(+)-2-Methyl-2-propanesulfinamide solution 1 M in THF, contains BHT as inhibitor
50ml
$ 63.00

Sigma-Aldrich
(R)-(+)-2-Methyl-2-propanesulfinamide solution 1 M in THF, contains BHT as inhibitor
10ml
$ 25.30

Sigma-Aldrich
(R)-(+)-2-Methyl-2-propanesulfinamide 98%
25g
$ 684.00

Total 189 raw suppliers

Chemical Property of 2-Methylpropane-2-sulfinamide Edit

Chemical Property:

Appearance/Colour:white to light yellow crystal powder
Melting Point:103-107 °C(lit.)
Refractive Index:4 ° (C=1, CHCl3)
Boiling Point:219.957 °C at 760 mmHg
PKA:10.11±0.50(Predicted)
Flash Point:86.827 °C
PSA：62.30000
Density:1.124 g/cm³
LogP:1.97330
Storage Temp.:Keep Cold
Solubility.:Soluble in chloroform, methanol, tetrahydrofuran, dichloromethan
XLogP3:0
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:121.05613515
Heavy Atom Count:7
Complexity:84.2

Purity/Quality:

99% ^*data from raw suppliers

(R)-tert-Butylsulfinamide ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,Xn,F
Statements: 11-19-36/37-40-36/37/38
Safety Statements: 22-24/25-36/37-26-16-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)S(=O)N
Uses suzuki reaction, useful reagent for synthesizing chiral amines. (R)-(+)-2-Methyl-2-propanesulfinamide is a chiral ligand, which is used in pharmaceutical compositions. Further, it is used in the preparation of beta-chloro sulfinamides in the synthesis of chiral azridines. It is involved in the preparation of organocatalyst for enantioselective reduction of imines. It serves as a reagent for synthesizing chiral amines. In addition to this, it is converted into P,N-sulfinyl imine ligands through condensation with aldehydes and ketones which undergoes iridium-catalyzed asymmetric hydrogenation of olefins. Chiral ligand used in pharmaceutical compositions

Technology Process of 2-Methylpropane-2-sulfinamide

There total 28 articles about 2-Methylpropane-2-sulfinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 441788-45-0
(R_S,S)-N-(3-hydroxy-1,3-diphenylpropylidene)-tert-butanesulfinamide

: 42052-51-7,69897-46-7,72237-27-5,93059-59-7
(S)-3-hydroxy-1,3-diphenyl-propan-1-one

: 196929-78-9
(R)-2-methylpropane-2-sulfinamide

Guidance literature:: With acetic acid; In methanol; at 40 ℃; for 20h;
DOI:10.1021/ja0363462

Reference yield: 98.0%

: 441788-43-8
(R_S,S)-N-(3-hydroxy-4-methyl-1-phenylpentylidene)-tert-butanesulfinamide

: (S)-3-hydroxy-4-methyl-1-phenyl-1-pentanoate

: 196929-78-9
(R)-2-methylpropane-2-sulfinamide

Guidance literature:: With acetic acid; In methanol; at 40 ℃; for 20h;
DOI:10.1021/ja0363462

Reference yield: 92.0%

: 159263-57-7
(R)-3-deoxy-1,2:5,6-di-O-isopropylidene-α-D-glucofuranos-3-yl tert-butanesulfinate

: 196929-78-9
(R)-2-methylpropane-2-sulfinamide

Guidance literature:: (R)-3-deoxy-1,2:5,6-di-O-isopropylidene-α-D-glucofuranos-3-yl tert-butanesulfinate; With lithium hexamethyldisilazane; In tetrahydrofuran; at 0 ℃; for 48h; Inert atmosphere;

With silica gel; In tetrahydrofuran; methanol; for 0.25h; Inert atmosphere;
DOI:10.1002/ejoc.201402673