1,2-Bis(3,5-di-tert-butyl-4-hydroxyhydrocinnamoyl)hydrazine

Base Information

• Chemical Name: 1,2-Bis(3,5-di-tert-butyl-4-hydroxyhydrocinnamoyl)hydrazine
• CAS No.: 32687-78-8
• Deprecated CAS: 77137-59-8,393567-12-9,2197022-96-9,2241586-69-4,393567-12-9
• Molecular Formula: C34H52N2O4
• Molecular Weight: 552.798
• Hs Code.: 2928000090
• European Community (EC) Number: 251-156-3
• UNII: Q4267VWT5Y
• DSSTox Substance ID: DTXSID6027979
• Nikkaji Number: J30.792K
• Wikidata: Q27286967
• Mol file: 32687-78-8.mol

Synonyms:32687-78-8;Antioxidant 1024;1,2-bis(3,5-di-tert-butyl-4-hydroxyhydrocinnamoyl)hydrazine;Irganox MD 1024;Irganox 1024;3-(3,5-di-tert-butyl-4-hydroxyphenyl)-N'-[3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl]propanehydrazide;Icganox 1024;2',3-Bis[[3-[3,5-di-tert-butyl-4-hydroxyphenyl]propionyl]]propionohydrazide;EINECS 251-156-3;3-(3,5-ditert-butyl-4-hydroxyphenyl)-N'-[3-(3,5-ditert-butyl-4-hydroxyphenyl)propanoyl]propanehydrazide;MD 1024;UNII-Q4267VWT5Y;Q4267VWT5Y;N,N'-Bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionyl)hydrazine;3-(3,5-di-tert-butyl-4-hydroxyphenyl)-N'-(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl)propanehydrazide;Benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-, 2-(3-(3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)-1-oxopropyl)hydrazide;Benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-, 2-[3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-1-oxopropyl]hydrazide;Bis(3,5-di-tert-butyl-4-hydroxyhydrocinnamoyl)hydrazine;3,5-Bis(1,1-dimethylethyl)-4-hydroxybenzenepropionic acid;1,2-Bis(3,5-di-tert-butyl-4-hydroxyhydrocinnamoyl)hydrazide;Hydrazine, 1,2-bis(3,5-di-tert-butyl-4-hydroxyhydrocinnamoyl)-;N,N'-Bis(3-(3',5'-di-tert-butyl-4'-hydroxyphenyl)propionyl)hydrazine;2',3-Bis((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionyl))propionohydrazide;2-(3-(3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl)-1-oxopropyl)hydrazide;EC 251-156-3;1,2-Bis(3,5-bis(tert-butyl)-4-hydroxyhydrocinnamoyl)hydrazide;Antioxidant MD-1024;1,2-Bis[3,5-bis(tert-butyl)-4-hydroxyhydrocinnamoyl]hydrazide;3-(3,5-di-tert-butyl-4-hydroxyphenyl)-N'-[3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl]propanohydrazide;Irganox MD-1024;LOWINOX MD 24;ADK STAB CDA 10;IRGANOX MD 2014;SCHEMBL39122;DTXSID6027979;MFCD00072662;AKOS016009467;HY-136941;LS-179542;CS-0135436;D5516;FT-0656477;D90401;EN300-154136;A821372;W-106829;Q27286967;1,2-bis (3,5-di-t-butyl-4-hydroxyhydrocinnamoyl) hydrazine;N,N'-bis(3,5-di-t-butyl-4-hydroxyphenylpropionyl)-hydrazine;N,N'-di(3,5-di-tert-butyl-4-hydroxyphenylpropionyl)hydrazine;N,N'-Bis(3(3,5-di-tert.-butyl-4-hydroxyphenyl)-propionyl)hydrazin;N,N'-bis-(3,5-di-tert-butyl-4-hydroxyphenyl-propionyl)-hydraz ine;1,2-BIS(3,5-DI-TERT-BUTYL-4- HYDROXYHYDROCINNAMOYL)HYDRAZINE;N,N'-BIS(.BETA.-(3,5-DI-TERT-BUTYL-4-HYDROXYPHENYL)PROPIONIC ACID) HYDRAZIDE;3,5-BIS(1,1-DIMETHYLETHYL)-4-HYDROXYBENZENEPROPIONIC ACID 2-(3-(3,5-BIS(1,1-DIMETHYLETHYL)-4-HYDROXYPHENYL)-1-OXOPROPYL)HYDRAZIDE;3-(3,5-Ditert-butyl-4-hydroxyphenyl)-N'-[3-(3,5-ditert-butyl-4-hydroxyphenyl)propanoyl]propanohydrazide #;Benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-, 2-[3-[3,5-bis(1,1-dimethylethyl) -4-hydroxyphenyl]-1-oxopropyl]hydrazide;Benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-,2-[3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-1-oxopropyl]hydrazide

Chemical Property of 1,2-Bis(3,5-di-tert-butyl-4-hydroxyhydrocinnamoyl)hydrazine

Chemical Property:

• Appearance/Colour: White powder
• Vapor Pressure: 1.24E-17mmHg at 25°C
• Melting Point: 60-67 °C
• Refractive Index: 1.535
• Boiling Point: 652.6 °C at 760 mmHg
• PKA: 11.10±0.50(Predicted)
• Flash Point: 348.48 °C
• PSA: 98.66000
• Density: 1.054 g/cm³
• LogP: 7.78240
• Storage Temp.: Refrigerator, under inert atmosphere
• Solubility.: Acetonitrile (Slightly), Chloroform (Slightly)
• XLogP3: 8.8
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 10
• Exact Mass: 552.39270814
• Heavy Atom Count: 40
• Complexity: 724

Purity/Quality:

99% ^*data from raw suppliers

1,2-Bis(3,5-di-tert-butyl-4-hydroxyhydrocinnamoyl)hydrazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)CCC(=O)NNC(=O)CCC2=CC(=C(C(=C2)C(C)(C)C)O)C(C)(C)C
• Description: FDA approve antioxidant 1024 usage in packaging polymers, resins, and adhesives intended for food contact applications. It is approved in many countries for food contact applications.
• Uses: Antioxidant 1024 is used in conjunction with phenolic antioxidants, phosphites/phosphonites, thio-synergists and other co-additives.

Technology Process of 1,2-Bis(3,5-di-tert-butyl-4-hydroxyhydrocinnamoyl)hydrazine

There total 4 articles about 1,2-Bis(3,5-di-tert-butyl-4-hydroxyhydrocinnamoyl)hydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.8%

3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoic acid hydrazide (32687-77-7) → N,N'-bis-[3-(3,5-di-t-butyl-4-hydroxyphenyl)propionyl]hydrazine (32687-78-8)

Guidance literature:

With ethyl acetoacetate; In methanol; toluene; at 85 ℃; for 3h; Temperature; Inert atmosphere;

Reference yield: 50.0%

3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoic acid hydrazide (32687-77-7) + 4-hydroxy-3,5-di-tert-butylphenylpropionic acid (20170-32-5,90804-34-5) → N,N'-bis-[3-(3,5-di-t-butyl-4-hydroxyphenyl)propionyl]hydrazine (32687-78-8)

Guidance literature:

In 5,5-dimethyl-1,3-cyclohexadiene; at 138 ℃; for 10h; Inert atmosphere;

Reference yield:

methyl 3-(4-hydroxy-3,5-di-tert-butyl)phenylpropanoate (6386-38-5) → N,N'-bis-[3-(3,5-di-t-butyl-4-hydroxyphenyl)propionyl]hydrazine (32687-78-8)

Guidance literature:

With hydrazine hydrate; sodium t-butanolate; In 5,5-dimethyl-1,3-cyclohexadiene; for 8h; Reagent/catalyst; Solvent; Heating;

upstream raw materials:

3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoic acid hydrazide

methyl 3-(4-hydroxy-3,5-di-tert-butyl)phenylpropanoate

4-hydroxy-3,5-di-tert-butylphenylpropionic acid

Refernces

• 1、 -. "A process for the preparation of hindered phenol antioxidant". Paragraph 0027; 0028. . Retrieved 2017/03/17.
• 2、 -. "COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS". . . Retrieved 2011/01/05.