DL-Pantolactone

Base Information Edit

Chemical Name:DL-Pantolactone
CAS No.:79-50-5
Deprecated CAS:52126-90-6
Molecular Formula:C6H10O3
Molecular Weight:130.144
Hs Code.:29322090
European Community (EC) Number:201-210-7
NSC Number:135788,8114,8113,5926
UNII:IID733HD2M
DSSTox Substance ID:DTXSID40861637
Nikkaji Number:J880.689F
Wikidata:Q22829045
ChEMBL ID:CHEMBL4066633
Mol file:79-50-5.mol

Synonyms:2,4-dihydroxy-3,3-dimethylbutyric acid gamma-lactone;pantolactone;pantolactone, (R)-isomer;pantolactone, (S)-isomer;pantolactone, 2-(14)C-labeled cpd, (+,-)-isomer;pantoyl lactone

Suppliers and Price of DL-Pantolactone

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(±)-Dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone
250g
$ 510.00

TRC
(±)-Dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone
50g
$ 120.00

TCI Chemical
DL-Pantolactone >95.0%(GC)
25g
$ 49.00

TCI Chemical
DL-Pantolactone >95.0%(GC)
100g
$ 110.00

TCI Chemical
DL-Pantolactone >95.0%(GC)
500g
$ 307.00

Sigma-Aldrich
Pantolactone United States Pharmacopeia (USP) Reference Standard
500 mg
$ 1120.00

Sigma-Aldrich
Pantolactone Pharmaceutical Secondary Standard; Certified Reference Material
500 mg
$ 130.00

Sigma-Aldrich
Pantolactone European Pharmacopoeia (EP) Reference Standard
$ 128.00

Sigma-Aldrich
DL-α-Hydroxy-β,β-dimethyl-γ-butyrolactone purum, ≥97.0% (T)
50g
$ 85.50

Sigma-Aldrich
DL-α-Hydroxy-β,β-dimethyl-γ-butyrolactone purum, ≥97.0% (T)
250g
$ 245.00

Total 87 raw suppliers

Chemical Property of DL-Pantolactone Edit

Chemical Property:

Appearance/Colour:White needles.
Melting Point:74-78 °C(lit.)
Boiling Point:224.6 °C at 760 mmHg
PKA:13.12±0.40(Predicted)
Flash Point:99 °C
PSA：49.83000
Density:1.165 g/cm³
LogP:-0.06970
Storage Temp.:Sealed in dry,Room Temperature
Solubility.:H2O: soluble1g/10 mL, clear, colorless to almost colorless
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:130.062994177
Heavy Atom Count:9
Complexity:139

Purity/Quality:

99.9% ^*data from raw suppliers

(±)-Dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 36/37/38
Safety Statements: 22-24/25-37/39-26

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Biological Agents -> Vitamins and Derivatives
Canonical SMILES:CC1(COC(=O)C1O)C
Uses DL-α-Hydroxy-β,β-dimethyl-γ-butyrolactone (DL-pantolactone) may be used in the preparation of 3,5-dinitrobenzoyl-DL-pantolactone.

Technology Process of DL-Pantolactone

There total 109 articles about DL-Pantolactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: C₇H₁₂O₂

: 79-50-5,599-04-2,5405-40-3,52126-90-6
(S)-pantolactone

Guidance literature:: With sodium tetrahydroborate; In acetic acid; for 0.5h;
DOI:10.1021/acs.joc.9b01426

Reference yield: 95.0%

: 13031-04-4
ketopantolactone

: 79-50-5,599-04-2,5405-40-3,52126-90-6
(S)-pantolactone

: 599-04-2
(R)-Pantolacton

Guidance literature:: With hydrogen; chloro(1,5-cyclooctadiene)rhodium(I) dimer; (2S,4S)-N-butoxycarbonyl-4-diphenylphosphino-2-diphenylphosphinomethylpyrrolidine; In toluene; at 50 ℃; for 45h; under 37503 Torr; Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1007/BF00816861