Technology Process of 2-Azaspiro[4.5]decan-3-one
There total 41 articles about 2-Azaspiro[4.5]decan-3-one which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
[1-(2-amino-2-oxoethyl)cyclohexyl]acetic acid;
With
sodium hydroxide; sodium hypochlorite;
In
water;
at 0 - 40 ℃;
for 3.5h;
With
hydrogenchloride;
In
water;
at 100 - 105 ℃;
for 3h;
pH=8.2 - 8.8;
Product distribution / selectivity;
Heating / reflux;
- Guidance literature:
-
(1-cyanocyclohexyl)-acetic acid;
With
sodium hydroxide;
In
water;
pH=12;
With
hydrogen;
In
water; toluene;
at 80 - 85 ℃;
under 3750.38 - 7500.75 Torr;
Inert atmosphere;
- Guidance literature:
-
(1-cyanocyclohexyl)acetonitrile;
With
sodium hydrogencarbonate;
at 25 ℃;
for 28h;
pH=7.4 - 7.5;
Enzymatic reaction;
With
sodium hydroxide;
In
water;
at 20 ℃;
With
hydrogen;
In
water;
at 80 ℃;
under 7500.75 Torr;
Concentration;
Time;
Inert atmosphere;
