C₆₅H₁₁₂N₁₀O₁₆

Base Information

• Chemical Name: C₆₅H₁₁₂N₁₀O₁₆
• CAS No.: 1191932-85-0
• Molecular Formula: C₆₅H₁₁₂N₁₀O₁₆
• Molecular Weight: 1289.66
• Mol file: 1191932-85-0.mol

Synonyms:C₆₅H₁₁₂N₁₀O₁₆

Chemical Property of C₆₅H₁₁₂N₁₀O₁₆

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of C₆₅H₁₁₂N₁₀O₁₆

There total 3 articles about C₆₅H₁₁₂N₁₀O₁₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C13H14Cl2N2O4 (1191932-84-9) + 4,7-bis-tertbutoxycarbonylmethyl-1,4,7,10-tetraazacyclododec-1-yl acetic acid tertbutyl ester hydrobromide → C65H112N10O16 (1191932-85-0)

Guidance literature:

4,7-bis-tertbutoxycarbonylmethyl-1,4,7,10-tetraazacyclododec-1-yl acetic acid tertbutyl ester hydrobromide; With N,N,N',N'-tetramethylguanidine; In dichloromethane; for 2h;

C₁₃H₁₄Cl₂N₂O₄; With N-ethyl-N,N-diisopropylamine; In acetonitrile; for 24h; Inert atmosphere; Reflux;

Reference yield:

ethyl 3,5-dinitrobenzoate (618-71-3) → C65H112N10O16 (1191932-85-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: hydrogenchloride; hydrogen / palladium 10% on activated carbon / ethanol; water / 20 h / 6750.68 Torr / Buchi reactor

2.1: acetonitrile / Inert atmosphere

2.2: pH 7 / Inert atmosphere; Cooling with ice

3.1: N,N,N',N'-tetramethylguanidine / dichloromethane / 2 h

3.2: 24 h / Inert atmosphere; Reflux

With hydrogenchloride; hydrogen; N,N,N',N'-tetramethylguanidine; palladium 10% on activated carbon; In ethanol; dichloromethane; water; acetonitrile;

Reference yield:

3,5-diamino-benzoic acid ethyl ester; hydrochloride (1949-52-6) → C65H112N10O16 (1191932-85-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: acetonitrile / Inert atmosphere

1.2: pH 7 / Inert atmosphere; Cooling with ice

2.1: N,N,N',N'-tetramethylguanidine / dichloromethane / 2 h

2.2: 24 h / Inert atmosphere; Reflux

With N,N,N',N'-tetramethylguanidine; In dichloromethane; acetonitrile;

upstream raw materials:

C₁₃H₁₄Cl₂N₂O₄

ethyl 3,5-dinitrobenzoate

3,5-diamino-benzoic acid ethyl ester; hydrochloride

Downstream raw materials:

C₆₇H₁₁₆N₁₀O₁₆

Refernces