Technology Process of 2R-(2-acetoxyethyl)-3-cyclopenten-1S-ol
There total 1 articles about 2R-(2-acetoxyethyl)-3-cyclopenten-1S-ol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: lithium aluminium tetrahydride / diethyl ether / 1.5 h / 0 °C / Inert atmosphere
2: 2,4,6-trimethyl-pyridine / dichloromethane / 7 h / -78 °C / Inert atmosphere
With
2,4,6-trimethyl-pyridine; lithium aluminium tetrahydride;
In
diethyl ether; dichloromethane;
DOI:10.1021/jm1012787
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: 2,6-dimethylpyridine / dichloromethane / 0.17 h / -78 °C / Inert atmosphere
2.1: potassium carbonate / methanol / 2 h / 23 °C
3.1: ozone / dichloromethane / 0.08 h / -78 °C / Inert atmosphere
3.2: 2 h / 0 °C / Inert atmosphere
4.1: triethylsilane; boron trifluoride diethyl etherate / dichloromethane / 0.17 h / 0 °C / Inert atmosphere
5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 23 °C
6.1: pyridine / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere
With
pyridine; 2,6-dimethylpyridine; triethylsilane; boron trifluoride diethyl etherate; tetrabutyl ammonium fluoride; potassium carbonate; ozone;
In
tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jm1012787
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: 2,6-dimethylpyridine / dichloromethane / 0.17 h / -78 °C / Inert atmosphere
2.1: potassium carbonate / methanol / 2 h / 23 °C
3.1: ozone / dichloromethane / 0.08 h / -78 °C / Inert atmosphere
3.2: 2 h / 0 °C / Inert atmosphere
4.1: triethylsilane; boron trifluoride diethyl etherate / dichloromethane / 0.17 h / 0 °C / Inert atmosphere
5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 23 °C
6.1: pyridine / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere
7.1: triethylamine / acetonitrile / 0 - 23 °C / Inert atmosphere
With
pyridine; 2,6-dimethylpyridine; triethylsilane; boron trifluoride diethyl etherate; tetrabutyl ammonium fluoride; potassium carbonate; ozone; triethylamine;
In
tetrahydrofuran; methanol; dichloromethane; acetonitrile;
DOI:10.1021/jm1012787