2-Cyclohexyl-2-hydroxy-2-phenylacetic acid

Base Information Edit

Chemical Name:2-Cyclohexyl-2-hydroxy-2-phenylacetic acid
CAS No.:4335-77-7
Molecular Formula:C₁₄H₁₈O₃
Molecular Weight:234.295
Hs Code.:29181990
European Community (EC) Number:224-380-4
NSC Number:93969,28945
UNII:QH762W903U
DSSTox Substance ID:DTXSID50863369
Nikkaji Number:J1.824.762C,J205.717D
Wikidata:Q27287264
Metabolomics Workbench ID:87202
ChEMBL ID:CHEMBL1333063
Mol file:4335-77-7.mol

Synonyms:4335-77-7;2-cyclohexyl-2-hydroxy-2-phenylacetic acid;alpha-Cyclohexylmandelic acid;Cyclohexylphenylglycolic acid;Cyclohexyl-hydroxy-phenyl-acetic acid;Hexahydrobenzilic acid;Cyclohexylmandelic acid;50896-04-3;2-cyclohexyl-2-hydroxy-phenylacetic acid;alpha-Cyclohexyl-DL-mandelic Acid;phenylcyclohexylglycolic acid;Phenyl-cyclohexylglycolic acid;RCC 32;(+-)-Cyclohexylphenylglycolic acid;a-cyclohexylmandelic acid;alpha-Phenylcyclohexaneglycolic acid;cyclohexyl(hydroxy)phenylacetic acid;EINECS 224-380-4;KL-007-M1;NSC 28945;NSC 93969;UNII-QH762W903U;2-Cyclohexyl-2-hydroxy-2-phenyl-acetic acid;Acide phenylcyclohexylhydroxyacetique [French];alpha-Cyclohexyl-alpha-hydroxybenzeneacetic acid;QH762W903U;2-cyclohexyl-2-phenylglycolic acid;Acide phenylcyclohexylhydroxyacetique;Benzeneacetic acid, alpha-cyclohexyl-alpha-hydroxy-;MFCD00194543;NSC-28945;NSC-93969;Cyclohexaneglycolic acid, alpha-phenyl-;(RS)-2-Cyclohexyl-2-hydroxy-2-phenylacetic Acid (Phenylcyclohexylglycolic Acid);CPGA;cyclohexyl mandelic acid;Benzeneacetic acid, a-cyclohexyl-a-hydroxy-;ChemDiv2_000672;alpha cyclohexylmandelic acid;Oprea1_543150;cyclohexylphenyl glycolic acid;MLS001211653;SCHEMBL198082;RCC-32;CHEMBL1333063;DTXSID50863369;alpha-cyclohexylphenylglycolic acid;CHEBI:165187;HMS1370O12;HMS2833F08;alpha-Cyclohexylmandelic acid, 97%;BCP22302;Cyclohexyl-hydroxy-phenylacetic acid;NSC28945;NSC93969;STK364404;AKOS000300197;AKOS016842341;CCG-106579;CS-O-15298;DS-1292;a-cyclohexyl-a-hydroxyphenyl acetic acid;cyclohexyl (hydroxy) phenyl acetic acid;NCGC00245367-01;AC-16189;LS-56861;SMR000518539;SY011590;2-cyclohexyl-2-hydroxy-2-phenylaceticacid;Benzeneacetic acid,a-cyclohexyl-a-hydroxy-;.ALPHA.-CYCLOHEXYL-DL-MANDELIC ACID;.ALPHA.-PHENYLCYCLOHEXYLGLYCOLIC ACID;2-cyclohexyl-2-hydroxy-2-phenyl acetic acid;AM20040469;C2393;CS-0156519;FT-0635236;FT-0665345;FT-0665346;EN300-7392541;AE-641/03292035;W-106234;(aS)-alpha-Hydroxy-alpha-cyclohexylbenzeneacetic acid;.ALPHA.-CYCLOHEXYL-.ALPHA.-PHENYLGLYCOLIC ACID;BRD-A49752073-001-07-3;Q27287264;OXYBUTYNIN HYDROCHLORIDE IMPURITY D [EP IMPURITY];Z1741965610;Benzeneacetic acid, alpha-cyclohexyl-alpha-hydroxy- (9CI);BENZENEACETIC ACID, .ALPHA.-CYCLOHEXYL-.ALPHA.-HYDROXY-

Suppliers and Price of 2-Cyclohexyl-2-hydroxy-2-phenylacetic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Cyclohexyl-2-hydroxy-phenylaceticAcid
20g
$ 245.00

TRC
2-Cyclohexyl-2-hydroxy-phenylaceticAcid
1g
$ 65.00

TCI Chemical
alpha-Cyclohexyl-DL-mandelic Acid >98.0%(HPLC)(T)
5g
$ 64.00

TCI Chemical
alpha-Cyclohexyl-DL-mandelic Acid >98.0%(HPLC)(T)
25g
$ 192.00

Sigma-Aldrich
α-Cyclohexylmandelic acid 97%
25g
$ 260.00

Sigma-Aldrich
Oxybutynin Related Compound A United States Pharmacopeia (USP) Reference Standard
100mg
$ 1260.00

Sigma-Aldrich
α-Cyclohexylmandelic acid 97%
5g
$ 82.70

Matrix Scientific
Cyclohexyl-hydroxy-phenyl-acetic acid
500mg
$ 174.00

Frontier Specialty Chemicals
alpha-Cyclohexylmandelicacid 98%
25g
$ 293.00

Frontier Specialty Chemicals
alpha-Cyclohexylmandelicacid 98%
1g
$ 24.00

Total 107 raw suppliers

Chemical Property of 2-Cyclohexyl-2-hydroxy-2-phenylacetic acid Edit

Chemical Property:

Appearance/Colour:white crystal powder
Vapor Pressure:2.08E-07mmHg at 25°C
Melting Point:163 °C
Boiling Point:408.6 °C at 760 mmHg
PKA:3.49±0.25(Predicted)
Flash Point:215.1 °C
PSA：57.53000
Density:1.206 g/cm³
LogP:2.53910
Storage Temp.:-20°C Freezer
XLogP3:3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:234.125594432
Heavy Atom Count:17
Complexity:265

Purity/Quality:

99.0%min ^*data from raw suppliers

2-Cyclohexyl-2-hydroxy-phenylaceticAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 37/38-41
Safety Statements: 26-39

MSDS Files:

Useful:

Canonical SMILES:C1CCC(CC1)C(C2=CC=CC=C2)(C(=O)O)O
Description This indole alkaloid occurs in the leaves of Lespedeza bicolor var. japonica and, when pure, is a colourless oil. Its MeOH solution, the ultraviolet spectrum exhibits absorption maxima at 223.4, 279 and 291 mJi. The crystalline hydrochloride has m.p. 163-4°C (dec.); the picrate forms long, yellow needles from MeOH, m.p. 160-2°C (dec.) and the styphnate, also yellow needles, has m.p. 170°C (dec.). The structure has been established as 3-(dimethylaminoethyl)-1-methoxyindole.
Uses An intermediate in the synthesis of oxybutynin (O868525). intermediate for Oxybutynin HCl, Oxyphenonium Bromide An intermediate in the synthesis of oxybutynin (O868525). Oxybutynin USP Related Compound A.

Technology Process of 2-Cyclohexyl-2-hydroxy-2-phenylacetic acid

There total 27 articles about 2-Cyclohexyl-2-hydroxy-2-phenylacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.5%