3-(6-(4-bromophenoxy)hexyloxy)-2-pyridine carboxylic acid methyl ester

Base Information

• Chemical Name: 3-(6-(4-bromophenoxy)hexyloxy)-2-pyridine carboxylic acid methyl ester
• CAS No.: 1389318-33-5
• Molecular Formula: C₁₉H₂₂BrNO₄
• Molecular Weight: 408.292
• Mol file: 1389318-33-5.mol

Synonyms:3-(6-(4-bromophenoxy)hexyloxy)-2-pyridine carboxylic acid methyl ester

Chemical Property of 3-(6-(4-bromophenoxy)hexyloxy)-2-pyridine carboxylic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 3-(6-(4-bromophenoxy)hexyloxy)-2-pyridine carboxylic acid methyl ester

There total 6 articles about 3-(6-(4-bromophenoxy)hexyloxy)-2-pyridine carboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

methyl 3-hydroxypicolinate (62733-99-7) + 1-bromo-4-(6-bromohexyloxy)benzene (75612-73-6) → 3-(6-(4-bromophenoxy)hexyloxy)-2-pyridine carboxylic acid methyl ester (1389318-33-5)

Guidance literature:

With potassium carbonate; potassium iodide; In acetone; at 80 ℃; for 24h; Inert atmosphere;

DOI:10.1002/asia.201200182

Reference yield: 66.0%

4-bromo-phenol (106-41-2) + 3-(6-bromohexyloxy)-2-pyridine carboxylic acid methyl ester (1292722-77-0) → 3-(6-(4-bromophenoxy)hexyloxy)-2-pyridine carboxylic acid methyl ester (1389318-33-5)

Guidance literature:

With potassium carbonate; potassium iodide; In acetone; for 48h; Reflux; Inert atmosphere;

Reference yield:

1 ,6-dibromohexane (629-03-8) → 3-(6-(4-bromophenoxy)hexyloxy)-2-pyridine carboxylic acid methyl ester (1389318-33-5)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / acetone / 24 h / 80 °C / Inert atmosphere

2: potassium carbonate; potassium iodide / acetone / 24 h / 80 °C / Inert atmosphere

With potassium carbonate; potassium iodide; In acetone; 2: |Williamson Ether Synthesis;

DOI:10.1002/asia.201200182

upstream raw materials:

1 ,6-dibromohexane

methyl 3-hydroxypicolinate

1-bromo-4-(6-bromohexyloxy)benzene

4-bromo-phenol

Downstream raw materials:

3-(6-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)hexyloxy)-2-pyridine carboxylic acid methyl ester

Refernces

• 1、 Shi, Danyan,Wang, Yafei,Liu, Yu,Zhang, Zhiyong,Luo, Jian,He, Juan,Chen, Qing,Lei, Gangtie,Zhu, Weiguo. "Star-shaped trinuclear cyclometalated platinum(II) complexes as single-component emitters in white-emitting PLEDs". . p. 2096 - 2101. Retrieved 2012/10/29.