(S)-1-N-Boc-3-hydroxypyrrolidine

Base Information Edit

Chemical Name:(S)-1-N-Boc-3-hydroxypyrrolidine
CAS No.:101469-92-5
Molecular Formula:C9H17NO3
Molecular Weight:187.239
Hs Code.:29339900
DSSTox Substance ID:DTXSID00357541
Nikkaji Number:J1.006.140G
Wikidata:Q72449641
Mol file:101469-92-5.mol

Synonyms:101469-92-5;(S)-1-N-Boc-3-hydroxypyrrolidine;(S)-tert-butyl 3-hydroxypyrrolidine-1-carboxylate;(S)-1-Boc-3-hydroxypyrrolidine;tert-butyl (3S)-3-hydroxypyrrolidine-1-carboxylate;(S)-(+)-1-Boc-3-hydroxypyrrolidine;(S)-(+)-N-Boc-3-pyrrolidinol;(S)-N-Boc-3-pyrrolidinol;N-(tert-Butoxycarbonyl)-(S)-(+)-3-pyrrolidinol;(S)-1-(tert-Butoxycarbonyl)-3-pyrrolidinol;(S)-3-Hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester;(S)-1-(tert-Butoxycarbonyl)-3-hydroxypyrrolidine;(S)-1-Boc-3-pyrrolidinol;1-PYRROLIDINECARBOXYLIC ACID, 3-HYDROXY-, 1,1-DIMETHYLETHYL ESTER, (3S)-;(S)-(-)-N-BOC-3-PYRROLIDINOL;(S)-N-(tert-Butoxycarbonyl)-3-hydroxypyrrolidine;(s)-tert-butyl-3-hydroxypyrrolidine-1-carboxylate;(S)-3-Hydroxypyrrolidine-1-carboxylic acid tert-butyl ester;MFCD01317839;(S)-Boc-PL;BOC-(S)-3-pyrrolidinol;(S)-tert-butyl3-hydroxypyrrolidine-1-carboxylate;SCHEMBL14431;tert-butyl (S)-3-hydroxypyrrolidine-1-carboxylate;DTXSID00357541;(S)-3-hydroxy-N-Boc-pyrrolidine;N-Boc-(S)-(+)-3-pyrrolidinol;n-t-boc-(s)-3-hydroxypyrrolidine;CS-M0905;(3S)-1-BOC-3-PYRROLIDINOL;(S)-1-N-Boc-3-hydroxy-pyrrolidine;AKOS005258996;AC-2554;PB17202;(S)-(+)-N-Boc-3-pyrrolidinol, 97%;AS-37120;N-tert-butoxycarbonyl-3-(S)-pyrrolidinol;(3S)-N-tert-butoxycarbonylpyrrolidin-3-ol;(S)-3-hydroxypyrrolidine, n-boc protected;(S)-1-t-butoxycarbonyl-3-hydroxypyrrolidine;AM20070666;B3055;EN300-77160;(S)-1-tert-butoxycarbonyl-3-hydroxypyrrolidine;(S)-3-hydroxy-1-tert-butoxycarbonylpyrrolidine;(s)-n-tert-butoxycarbonyl-3-hydroxypyrrolidine;t-butyl(3S)-3-hydroxypyrrolidine-1-carboxylate;t-butyl (3S)-3-hydroxypyrrolidine-1-carboxylate;tert-butyl(S)-3-hydroxypyrrolidine-1-carboxylate;(5)-tert-butyl 3-hydroxypyrrolidine-1-carboxylate;(S)-N-(tert-Butoxycarbonyl)-(+)-3-pyrrolidinol;tert-Butyl(3S)-3-hydroxypyrrolidine-1-carboxylate;Q-102851;Q-102861;tert-butyl (S)-3-hydroxy-pyrrolidine-1-carboxylate;tert. butyl (S)-3-hydroxy-pyrrolidin-1-carboxylate;(3S)-1-TERT-BUTOXYCARBONYL-3-HYDROXYPYRROLIDINE;(S)-(+)-tert-butyl-3-hydroxypyrrolidine-1-carboxylate;Z1192367724;(S)-3-hydroxypyrrolidine-1-carboxylic acid t-butyl ester;1,1-dimethylethyl (35)-3-hydroxy-1-pyrrolidinecarboxylate;1,1-dimethylethyl (3S)-3-hydroxy-1-pyrrolidinecarboxylate;1,1-dimethylethyl(3S)-3-hydroxy-1-pyrrolidinecarboxylate;(3S)-3-hydroxy-1-pyrrolidinecarboxylic acid, 1,1-dimethylethyl ester

Suppliers and Price of (S)-1-N-Boc-3-hydroxypyrrolidine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-tert-Butyl3-hydroxypyrrolidine-1-carboxylate
1g
$ 75.00

TCI Chemical
(S)-1-(tert-Butoxycarbonyl)-3-pyrrolidinol >98.0%(GC)
5g
$ 56.00

TCI Chemical
(S)-1-(tert-Butoxycarbonyl)-3-pyrrolidinol >98.0%(GC)
1g
$ 38.00

SynQuest Laboratories
N-Boc-(S)-3-hydroxypyrrolidine 97%
1 g
$ 16.00

SynQuest Laboratories
N-Boc-(S)-3-hydroxypyrrolidine 97%
5 g
$ 24.00

SynChem
(S)-N-(tert-Butoxycarbonyl)-3-hydroxypyrrolidine 97+%, 98+%ee
10 g
$ 50.00

SynChem
(S)-N-(tert-Butoxycarbonyl)-3-hydroxypyrrolidine 97+%, 98+%ee
100 g
$ 260.00

Sigma-Aldrich
(S)-(+)-N-Boc-3-pyrrolidinol 97%
1g
$ 72.80

Sigma-Aldrich
(S)-(+)-N-Boc-3-pyrrolidinol 97%
5g
$ 31.90

Matrix Scientific
(S)-(+)-N-Boc-3-pyrrolidinol 95+%
25g
$ 24.00

Total 160 raw suppliers

Chemical Property of (S)-1-N-Boc-3-hydroxypyrrolidine Edit

Chemical Property:

Appearance/Colour:white to light yellow crystal powder
Vapor Pressure:0.000742mmHg at 25°C
Melting Point:60-64 °C
Refractive Index:27 ° (C=1, MeOH)
Boiling Point:273.3 °C at 760 mmHg
PKA:14.74±0.20(Predicted)
Flash Point:119.1 °C
PSA：49.77000
Density:1.142 g/cm³
LogP:0.92600
Storage Temp.:Store at 0-5°C
Solubility.:soluble in Methanol
XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:187.12084340
Heavy Atom Count:13
Complexity:198

Purity/Quality:

99% ^*data from raw suppliers

(S)-tert-Butyl3-hydroxypyrrolidine-1-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s): T,Xi
Hazard Codes:T,Xi
Statements: 25-37/38-41-R41-R37/38-R25
Safety Statements: 26-39-45-S45-S39-S26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCC(C1)O
Isomeric SMILES:CC(C)(C)OC(=O)N1CC[C@@H](C1)O
Uses (S)-(+)-N-Boc-3-pyrrolidinol can be used as a reactant to synthesize: tert-Butyl 3-(2-bromophenoxy)pyrrolidine-1-carboxylate, which is employed as a key intermediate in the preparation of IkB-kinase IKK2 inhibitor. Dimethoxy-pyrrolidylquinazoline , and peptidomimetic quinoline derivatives.

Technology Process of (S)-1-N-Boc-3-hydroxypyrrolidine

There total 17 articles about (S)-1-N-Boc-3-hydroxypyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%