1-Butylpiperazine

Base Information

• Chemical Name: 1-Butylpiperazine
• CAS No.: 5610-49-1
• Molecular Formula: C8H18 N2
• Molecular Weight: 142.244
• Hs Code.: 2933599090
• Mol file: 5610-49-1.mol

Synonyms:1-Butylpiperazine;N-Butylpiperazine

Chemical Property of 1-Butylpiperazine

Chemical Property:

• Vapor Pressure: 0.343mmHg at 25°C
• Melting Point: >240 °C
• Refractive Index: n20/D 1.466
• Boiling Point: 89 °C
• PKA: 9.27±0.10(Predicted)
• Flash Point: 69.6oC
• PSA: 15.27000
• Density: 0.866g/cm3
• LogP: 0.95840

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-Butylpiperazine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Butylpiperazine

There total 2 articles about 1-Butylpiperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ N-butylpiperazine (5610-49-1) + n-butyldiethanolamine (102-79-4)

Guidance literature:

Reference yield:

n-butyldiethanolamine (102-79-4) + ammonia (7664-41-7) → N-butylpiperazine (5610-49-1) + 2-butylamino-ethanol (111-75-1) + N-(2-aminoethyl)-N-butyl-1,2-ethanediamine (30935-67-2)

Guidance literature:

at 200 ℃; under 51485.6 Torr;

Reference yield: 88.0%

N-butylpiperazine (5610-49-1) + carbon disulfide (75-15-0,12122-00-8) + 4-bromo-2,2-diphenylbutyronitrile (39186-58-8) → 4-butyl-piperazine-1-carbodithioic acid 3-cyano-3,3-diphenyl-propyl ester

Guidance literature:

N-butylpiperazine; carbon disulfide; With potassium phosphate; In acetone; at 20 ℃; for 0.5h;

4-bromo-2,2-diphenylbutyronitrile; In acetone; at 20 ℃;

DOI:10.1016/j.bmcl.2006.05.085

upstream raw materials:

n-butyldiethanolamine

ammonia

Downstream raw materials:

1-butyl-4-(4-chloro-benzhydryl)-piperazine

1-(diphenylmethyl)-4-butylpiperazine

C₅₁H₆₄N₄O₁₃

PD 161654

Refernces