2,6-Difluorobenzenesulfonamide

Base Information

• Chemical Name: 2,6-Difluorobenzenesulfonamide
• CAS No.: 60230-37-7
• Molecular Formula: C6H5 F2 N O2 S
• Molecular Weight: 193.174
• Hs Code.: 2935009090
• Mol file: 60230-37-7.mol

Synonyms:2,6-Difluorobenzenesulfonamide

Chemical Property of 2,6-Difluorobenzenesulfonamide

Chemical Property:

• Vapor Pressure: 0.00065mmHg at 25°C
• Melting Point: 187-191 ºC
• Boiling Point: 309.2°C at 760 mmHg
• PKA: 9.31±0.60(Predicted)
• Flash Point: 140.8°C
• PSA: 68.54000
• Density: 1.523g/cm³
• LogP: 2.39330
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98% ^*data from raw suppliers

2,6-Difluorobenzenesulfonamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 24/25-37-26

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2,6-Difluorobenzenesulfonamide can be prepared from N-(4-chlorophenyl)-N′-[(2,6-di fluorophenyl)-sulfonyl]urea.

Technology Process of 2,6-Difluorobenzenesulfonamide

There total 3 articles about 2,6-Difluorobenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2,6-difluorobenzene-1-sulfonyl chloride (60230-36-6) → 2,6-difluorobenzene-1-sulfonamide (60230-37-7)

Guidance literature:

With ammonia; In tetrahydrofuran; at 0 - 20 ℃;

Reference yield:

2,6-difluorobenzene-1-sulfonyl chloride (60230-36-6) + 2,6-difluoroaniline (5509-65-9) → 2,6-difluorobenzene-1-sulfonamide (60230-37-7)

Guidance literature:

Reference yield:

→ 2,6-difluorobenzene-1-sulfonamide (60230-37-7)

Guidance literature:

Sulfonylchlorid (20), NH3;

DOI:10.1021/jf60207a051

upstream raw materials:

2,6-difluorobenzene-1-sulfonyl chloride

2,6-difluoroaniline

Downstream raw materials:

2,6-difluoro-N-methyl-benzenesulfonamide

Refernces

• 1、 -. "N-(phenylsulfonyl)picolinamide derivatives, process for producing the same, and herbicide". . . Retrieved 2008/06/13.