N-METHACRYLOYL-L-LYSINE

Base Information

• Chemical Name: N-METHACRYLOYL-L-LYSINE
• CAS No.: 45158-94-9
• Molecular Formula: C₁₀H₁₈N₂O₃
• Molecular Weight: 214.265
• Mol file: 45158-94-9.mol

Synonyms:N-Methacryloyl-L-lysine;

Chemical Property of N-METHACRYLOYL-L-LYSINE

Chemical Property:

• Boiling Point: 455.5 °C at 760 mmHg
• Flash Point: 229.3 °C
• PSA: 92.42000
• Density: 1.109 g/cm³
• LogP: 1.35210

Purity/Quality:

99% ^*data from raw suppliers

N-METHACRYLOYL-L-LYSINE 98.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-METHACRYLOYL-L-LYSINE

There total 6 articles about N-METHACRYLOYL-L-LYSINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

C20H34CuN4O6 → N-ε-methacryloyl lysine (112889-27-7,45158-94-9)

Guidance literature:

With thioacetamide; In water; for 0.333333h;

DOI:10.1002/pola.25063

Reference yield:

(S)-α-lysine hydrochloride (26124-78-7) + Methacryloyl chloride (920-46-7,26937-45-1) → C10H18N2O3 (45158-94-9,112889-27-7) + C10H18N2O3 (45159-28-2)

Guidance literature:

With potassium hydrogencarbonate; In water; acetone; for 2.16667h; Cooling with ice;

Reference yield:

L-Lysine hydrochloride (657-27-2,10098-89-2,26124-78-7) + Methacryloyl chloride (920-46-7,26937-45-1) → N-ε-methacryloyl lysine (112889-27-7,45158-94-9)

Guidance literature:

L-Lysine hydrochloride; With copper(II) carbonate; In water; at 90 ℃;

Methacryloyl chloride; With potassium hydroxide; In water; acetone; at 3 ℃;

With 8-quinolinol; In chloroform; water; Reflux;

DOI:10.1016/j.ijpharm.2011.09.001

upstream raw materials:

methacryloyl anhydride

L-Lysine hydrochloride

Methacryloyl chloride

(S)-α-lysine hydrochloride

Refernces

• 1、 Romanski, Jan,Karbarz, Marcin,Pyrzynska, Krystyna,Jurczak, Janusz,Stojek, Zbigniew. "Polymeric hydrogels modified with ornithine and lysine: Sorption and release of metal cations and amino acids". experimental part. p. 542 - 550. Retrieved 2012/04/23.