α,β-diphenyl-β-(p-ethylphenyl)ethylene

Base Information

• Chemical Name: α,β-diphenyl-β-(p-ethylphenyl)ethylene
• CAS No.: 86701-20-4
• Molecular Formula: C₂₂H₂₀
• Molecular Weight: 284.401
• Mol file: 86701-20-4.mol

Synonyms:α,β-diphenyl-β-(p-ethylphenyl)ethylene

Chemical Property of α,β-diphenyl-β-(p-ethylphenyl)ethylene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of α,β-diphenyl-β-(p-ethylphenyl)ethylene

There total 5 articles about α,β-diphenyl-β-(p-ethylphenyl)ethylene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

diphenyl acetylene (501-65-5) + sodium p-ethylbenzenesulfinic acid → α,β-diphenyl-β-(p-ethylphenyl)ethylene (86701-20-4)

Guidance literature:

With palladium diacetate; trifluoroacetic acid; naphthalene-1,8-diamine; In 1,4-dioxane; water; at 120 ℃; for 24h; stereoselective reaction; Inert atmosphere; Sealed tube;

DOI:10.1039/c3cc43723j

Reference yield:

1-bromo-4-ethylbenzene (1585-07-5) + diphenyl acetylene (501-65-5) → α,β-diphenyl-β-(p-ethylphenyl)ethylene (86701-20-4)

Guidance literature:

With diisobutylaluminium hydride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; Yield given. Multistep reaction; 1.) hexane, RT, 1 h, 55 deg C, 18 h; 2.) THF, reflux, 24 h;

DOI:10.1016/0022-328X(87)80330-3

Reference yield:

ethylbenzene (100-41-4,27536-89-6) → α,β-diphenyl-β-(p-ethylphenyl)ethylene (86701-20-4)

Guidance literature:

Multi-step reaction with 2 steps

1: AlCl₃; carbon disulfide

2: diethyl ether / Erwaermen des nach der Hydrolyse erhaltenen Reaktionsprodukts mit Acetylchlorid

With carbon disulfide; aluminium trichloride; diethyl ether;

upstream raw materials:

1-(4-ethylphenyl)-2-phenyl-1-ethanone

1-bromo-4-ethylbenzene

diphenyl acetylene

ethylbenzene

Downstream raw materials:

cis-broparestrol

BnBr

Refernces

• 1、 Al-Hassan, Mohammed I.. "Synthesis of Broparestrol using Palladium-Catalyzed Cross-coupling". . p. 119 - 122. Retrieved 2007/10/02.