N-(2-(Diethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide

Base Information Edit

Chemical Name:N-(2-(Diethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide
CAS No.:342641-94-5
Molecular Formula:C22H27FN4O2
Molecular Weight:398.48
Hs Code.:2933990090
Mol file:342641-94-5.mol

Synonyms:1H-PYRROLE-3-CARBOXAMIDE, N-[2-(DIETHYLAMINO)ETHYL]-5-[(5-FLUORO-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)METHYL]-2,4-DIMETHYL-(9CI);5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylicacid(2-diethylamino-ethyl)-amide;1H-PYRROLE-3-CARBOXAMIDE, N-[2-(DIETHYLAMINO)ETHYL]-5-[(5-FLUORO-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)METHYL]-2,4-DIMETHYL-;5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylicacid(2-diethylamino-ethyl)-am;N-(2-(Diethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide;1H-PYRROLE-3-CARBOXAMIDE, N-[2-(DIETHYLAMINO)ETHYL]-5-[(5-FLUORO-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)METHYL]-2,4-DIMETHYL-(9CI);N-[2-(Diethylamino)ethyl]-5-[(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide;1-[carbaMoyl(diethylaMino)Methyl]-5-[(5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene)Methyl]-2,4-diMethyl-1H-pyrrole-3-carboxylic acid

Suppliers and Price of N-(2-(Diethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
N-(2-(Diethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide 95+%
1g
$ 452.00

Chemenu
5-(5-FLUORO-2-OXO-1,2-DIHYDRO-INDOL-3-YLIDENEMETHYL)-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXYLICACID(2-DIETHYLAMINO-ETHYL)-AMIDE 95%
1g
$ 427.00

American Custom Chemicals Corporation
5-(5-FLUORO-2-OXO-1,2-DIHYDRO-INDOL-3-YLIDENEMETHYL)-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXYLIC ACID (2-DIETHYLAMINO-ETHYL)-AMIDE 95.00%
5MG
$ 502.83

Total 42 raw suppliers

Chemical Property of N-(2-(Diethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide Edit

Chemical Property:

Refractive Index:1.611
Boiling Point:572.136 °C at 760 mmHg
Flash Point:299.818 °C
PSA：77.23000
Density:1.23 g/cm³
LogP:3.86380

Purity/Quality:

99% ^*data from raw suppliers

N-(2-(Diethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N-(2-(Diethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide

There total 6 articles about N-(2-(Diethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.4%

: 56341-41-4
5-fluoroindol-2(3H)-one

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 590424-05-8
N-[2-(diethylamino)ethyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide

: 342641-94-5,326914-13-0
sunitinib

Guidance literature:: N,N-dimethyl-formamide; N-[2-(diethylamino)ethyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide; With phosgene; In acetonitrile; at 20 ℃;

5-fluoroindol-2(3H)-one; With potassium hydroxide; In acetonitrile; at 20 ℃; Product distribution / selectivity;

Reference yield:

: 452105-33-8
5-((5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

: 100-36-7
N,N-diethylethylenediamine

: 342641-94-5,326914-13-0
sunitinib

Guidance literature:: With TBTU; N-ethyl-N,N-diisopropylamine; In water; N,N-dimethyl-formamide; at 60 ℃; for 5h; Reagent/catalyst; Temperature; Solvent;