(R)-(-)-3-Hydroxytetrahydrofuran

Base Information Edit

Chemical Name:(R)-(-)-3-Hydroxytetrahydrofuran
CAS No.:86087-24-3
Molecular Formula:C4H8O2
Molecular Weight:88.1063
Hs Code.:29321900
UNII:AUS5N27VPH
Nikkaji Number:J146.587B
Mol file:86087-24-3.mol

Synonyms:86087-24-3;(R)-(-)-3-Hydroxytetrahydrofuran;(R)-TETRAHYDROFURAN-3-OL;(3R)-oxolan-3-ol;(R)-3-HYDROXYTETRAHYDROFURAN;(3R)-Tetrahydrofuran-3-ol;3-Furanol, tetrahydro-, (3R)-;84976-47-6;(3R)-tetrahydro-3-furanol;(R)-(-)-tetrahydrofuran-3-ol;MFCD00067101;(R)-(+)-3-Hydroxytetrahydrofuran;(R)-Tetrahydro-furan-3-ol;Tetrahydrofuran-3alpha-ol;AUS5N27VPH;(-)-3-Hydroxytetrahydrofuran;(R)-3-hydroxy-tetrahydrofuran;3-Hydroxytetrahydrofuran, (-)-;3-Hydroxytetrahydrofuran, (R)-;3-Furanol, tetrahydro-, (R)-;(-)-(r)-3-hydroxytetrahydrofuran;(3R)-(-)-3-Hydroxytetrahydrofuran;(R)-(-)-3-hydroxy tetrahydrofuran;(R)-(-)-3-hydroxy-tetrahydrofuran;BBL100951;STL554745;AKOS005256250;PS-9390;(R)-(-)-TETRAHYDRO-3-FURANOL;AC-13894;(R)-(-)-3-Hydroxytetrahydrofuran, 98%;AM20110237;CS-0045411;H1332;EN300-94223

Suppliers and Price of (R)-(-)-3-Hydroxytetrahydrofuran

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-(-)-3-Hydroxytetrahydrofuran
100g
$ 1425.00

TRC
(R)-(-)-3-Hydroxytetrahydrofuran
25g
$ 640.00

TRC
(R)-(-)-3-Hydroxytetrahydrofuran
1g
$ 80.00

TCI Chemical
(R)-3-Hydroxytetrahydrofuran >98.0%(GC)
1g
$ 109.00

TCI Chemical
(R)-3-Hydroxytetrahydrofuran >98.0%(GC)
5g
$ 380.00

SynQuest Laboratories
(3R)-3-Hydroxytetrahydrofuran
5 g
$ 135.00

SynQuest Laboratories
(3R)-3-Hydroxytetrahydrofuran
25 g
$ 500.00

SynQuest Laboratories
(3R)-3-Hydroxytetrahydrofuran
1 g
$ 75.00

Sigma-Aldrich
(R)-(?)-3-Hydroxytetrahydrofuran 98%
1g
$ 114.00

Medical Isotopes, Inc.
(R)-(-)-3-Hydroxytetrahydrofuran
100 g
$ 2175.00

Total 145 raw suppliers

Chemical Property of (R)-(-)-3-Hydroxytetrahydrofuran Edit

Chemical Property:

Appearance/Colour:colorless to light yellow liquid
Vapor Pressure:0.255mmHg at 25°C
Refractive Index:n20/D 1.45(lit.)
Boiling Point:181 °C at 760 mmHg
PKA:14.49±0.20(Predicted)
Flash Point:81.1 °C
PSA：29.46000
Density:1.148 g/cm³
LogP:-0.23240
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
Solubility.:Chloroform, Methanol (Slightly)
XLogP3:-0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:88.052429494
Heavy Atom Count:6
Complexity:44.8

Purity/Quality:

99%min ^*data from raw suppliers

(R)-(-)-3-Hydroxytetrahydrofuran ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCC1O
Isomeric SMILES:C1COC[C@@H]1O
Uses (R)-(-)-3-Hydroxytetrahydrofuran is used as a chemical reactant in the synthesis of pharmaceutical agents. Empagliflozin is synthesized using this reactant (R)-(-)-3-Hydroxytetrahydrofuran may be used as building block in the synthesis of potent HIV protease inhibitors.

Technology Process of (R)-(-)-3-Hydroxytetrahydrofuran

There total 19 articles about (R)-(-)-3-Hydroxytetrahydrofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.1%

: 125605-10-9
(3R)-4-chloro-1,3-butanediol

: 86087-24-3,84921-89-1,864447-89-2
(R)-3-Hydroxytetrahydrofuran

Guidance literature:: With hydrogenchloride; sodium hydroxide; In methanol; water;

Reference yield: 99.0%

: 70005-88-8,6810-31-7
(R)-1,2,4-butanetriol

: 86087-24-3,84921-89-1,864447-89-2
(R)-3-Hydroxytetrahydrofuran

Guidance literature:: strong acid ion exchange resin (Amberlyst 15, H+ form); In 1,4-dioxane; at 100 ℃; under 760.051 Torr; Product distribution / selectivity;