4,4',4''-Methylidenetrisbenzonitrile

Base Information

• Chemical Name: 4,4',4''-Methylidenetrisbenzonitrile
• CAS No.: 113402-31-6
• Molecular Formula: C₂₂H₁₃N₃
• Molecular Weight: 319.365
• Hs Code.: 2926909090
• Mol file: 113402-31-6.mol

Synonyms:4,4',4''-Methanetriyltribenzonitrile;

Chemical Property of 4,4',4''-Methylidenetrisbenzonitrile

Chemical Property:

• Boiling Point: 545.6 °C at 760 mmHg
• Flash Point: 262.2 °C
• PSA: 71.37000
• Density: 1.24 g/cm³
• LogP: 4.48184
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), Methanol (Sparingly)

Purity/Quality:

98%,99%, ^*data from raw suppliers

4,4'',4''''-Methylidynetrisbenzonitrile(LetrozoleImpurity) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 4,4'',4''''-Methylidynetrisbenzonitrile (Letrozole EP Impurity B) is a Letrozole isomeric impurity. Letrozole isomeric

Technology Process of 4,4',4''-Methylidenetrisbenzonitrile

There total 1 articles about 4,4',4''-Methylidenetrisbenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4,4',4''-tricyanotriphenylmethanol (117678-98-5) → 4,4',4''-tricyanotriphenylmethane (113402-31-6)

Guidance literature:

With triethylsilane; boron trifluoride diethyl etherate; In dichloromethane; at 20 ℃; for 6h;

DOI:10.1021/jacs.1c03882

upstream raw materials:

4,4',4''-tricyanotriphenylmethanol

Refernces