C₁₄H₁₂Cl₂N₂O

Base Information

• Chemical Name: C₁₄H₁₂Cl₂N₂O
• CAS No.: 845752-00-3
• Molecular Formula: C₁₄H₁₂Cl₂N₂O
• Molecular Weight: 295.168
• Mol file: 845752-00-3.mol

Synonyms:C₁₄H₁₂Cl₂N₂O

Chemical Property of C₁₄H₁₂Cl₂N₂O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₄H₁₂Cl₂N₂O

There total 2 articles about C₁₄H₁₂Cl₂N₂O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-amino-3-methylpyridine (1990-90-5,953018-16-1) → C14H12Cl2N2O (845752-00-3)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrogen bromide; dihydrogen peroxide / water / 2 h / 70 °C

2: triethylamine / toluene / 9 h / 110 °C

3: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,2-dimethoxyethane; water / 24 h / 85 °C

With hydrogen bromide; dihydrogen peroxide; sodium carbonate; triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; water; toluene;

Reference yield:

4-amino-5-bromo-3-methylpyridine (97944-43-9) → C14H12Cl2N2O (845752-00-3)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / toluene / 9 h / 110 °C

2: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,2-dimethoxyethane; water / 24 h / 85 °C

With sodium carbonate; triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; water; toluene;

Reference yield:

C14H12Cl2N2O (845752-00-3) + isopentyl nitrite (110-46-3) → C14H9Cl2N3O

Guidance literature:

With potassium acetate; acetic anhydride; In benzene; at 90 ℃; for 5.5h;

upstream raw materials:

4-amino-3-methylpyridine

4-amino-5-bromo-3-methylpyridine

Downstream raw materials:

C₁₂H₇Cl₂N₃

Refernces