(2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane

Base Information Edit

Chemical Name:(2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane
CAS No.:98760-08-8
Molecular Formula:C15H21NO3
Molecular Weight:263.337
Hs Code.:29242998
European Community (EC) Number:619-374-7,431-870-3,691-999-8
DSSTox Substance ID:DTXSID00431092
Nikkaji Number:J935.516B
Wikidata:Q72509784
Mol file:98760-08-8.mol

Synonyms:98760-08-8;(2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane;(2R,3S)-1,2-Epoxy-3-(Boc-amino)-4-phenylbutane;tert-Butyl ((S)-1-((R)-oxiran-2-yl)-2-phenylethyl)carbamate;(2R,3S)-3-(t-BOC)amino-1,2-epoxy-4-phenylbutane;tert-butyl N-[(1S)-1-[(2R)-oxiran-2-yl]-2-phenylethyl]carbamate;(2R,3S)-3-(tert-Boc)amino-1,2-epoxy-4-phenylbutane;TERT-BUTYL[(1S,2R)-OXIRANYL-2-PHENYLETHYL]CARBAMATE;(2R,3S)-3-(N-BOC-amino)-1-oxirane-4-phenylbutane;MFCD00671705;SCHEMBL639229;DTXSID00431092;NVPOUMXZERMIJK-STQMWFEESA-N;AMY33463;CS-B0126;tert-Butyl {(1S)-1-[(2R)-oxiran-2-yl]-2-phenylethyl}carbamate;AC-132;AC-206;AC7588;AKOS015908505;AS-15475;EN300-93022;(2R,3s)-3-BOC-amino-1,2-epoxy-4-phenylbutane;2(R)-[1(S)-(Boc-amino)-2-phenylethyl]-oxirane;Q-102797;Z1263823082;t-butyl[(s)-1-((r)-oxiran-2-yl)-2-phenylethyl]carbamate;(2R, 3S)-3-tert-butoxycarbonylamino-1,2-epoxy-4-phenylbutane;(2R,3S)-3-(t-butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane;N-tert-butoxycarbonyl-3(S)-amino-1,2(R)-epoxy-4-phenylbutane;tert-Butyl (1S)-1-[(2R)-oxiran-2-yl]-2-phenylethylcarbamate;tert-butyl (s)-1-((r)-oxiran-2-yl)-2-phenylethylcarbamate;tert-Butyl(1S)-1-[(2R)-oxiran-2-y1]-2-phenylethylcarbamate;tert-Butyl(1S)-1-[(2R)-oxiran-2-yl]-2-phenylethylcarbamate;[(alphaS,2R)-alpha-Benzylglycidyl]carbamic acid tert-butyl ester;N-(tert-butoxycarbonyl)-2(S)-amino-1-phenyl-3(R)-3,4-epoxybutane;tert-butyl N-{(1S)-1-[(2R)oxiran-2-yl]-2-phenylethyl}carbamate;tert-Butyl[s-(r*,r*)]-(-)-(1-oxiranyl-2-phenylethyl)carbamate

Suppliers and Price of (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2R,3S)-3-(tert-Boc)amino-1,2-epoxy-4-phenylbutane
2g
$ 90.00

SynQuest Laboratories
(2R,3S)-1,2-Epoxy-3-(Boc-amino)-4-phenylbutane
5 g
$ 228.00

Medical Isotopes, Inc.
(2R,3S)-3-(tert-Boc)amino-1,2-epoxy-4-phenylbutane
50 mg
$ 2200.00

JR MediChem
Carbamicacid,N-[(1S)-1-(2R)-2-oxiranyl-2-phenylethyl]-,1,1-dimethylethylester 96%
100g
$ 598.00

Crysdot
tert-Butyl((S)-1-((R)-oxiran-2-yl)-2-phenylethyl)carbamate 95%
100g
$ 297.00

Crysdot
tert-Butyl((S)-1-((R)-oxiran-2-yl)-2-phenylethyl)carbamate 95%
10g
$ 40.00

Crysdot
tert-Butyl((S)-1-((R)-oxiran-2-yl)-2-phenylethyl)carbamate 95%
25g
$ 89.00

Chem-Impex
threo-N-Boc-L-phenylalanineepoxide,≥99%(HPLC) ≥99%(HPLC)
1G
$ 13.50

Chem-Impex
threo-N-Boc-L-phenylalanineepoxide,99%(HPLC) 99%(HPLC)
5G
$ 26.60

Chem-Impex
threo-N-Boc-L-phenylalanineepoxide,≥99%(HPLC) ≥99%(HPLC)
25G
$ 88.52

Total 175 raw suppliers

Chemical Property of (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane Edit

Chemical Property:

Appearance/Colour:white crystalline powder
Vapor Pressure:0mmHg at 25°C
Refractive Index:1.533
Boiling Point:398.837 °C at 760 mmHg
PKA:12.19±0.46(Predicted)
Flash Point:195.01°C
PSA：50.86000
Density:1.118 g/cm³
LogP:2.91210
Storage Temp.:2-8°C
Solubility.:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:263.15214353
Heavy Atom Count:19
Complexity:305

Purity/Quality:

99% ^*data from raw suppliers

(2R,3S)-3-(tert-Boc)amino-1,2-epoxy-4-phenylbutane ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CC1=CC=CC=C1)C2CO2
Isomeric SMILES:CC(C)(C)OC(=O)N[C@@H](CC1=CC=CC=C1)[C@@H]2CO2
Uses Atazanavir intermediate. Enantiomer R Atazanavir, Amprenavir Intermediate

Technology Process of (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane

There total 154 articles about (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%