3-(bromomethyl)benzoyl bromide

Base Information

• Chemical Name: 3-(bromomethyl)benzoyl bromide
• CAS No.: 209743-33-9
• Molecular Formula: C₈H₆Br₂O
• Molecular Weight: 277.943
• Mol file: 209743-33-9.mol

Synonyms:3-(bromomethyl)benzoyl bromide

Chemical Property of 3-(bromomethyl)benzoyl bromide

Chemical Property:

• Boiling Point: 130°C/4.5mm

Purity/Quality:

98%min ^*data from raw suppliers

3-(Bromomethyl)benzoyl bromide 97% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi,C

MSDS Files:

Useful:

Technology Process of 3-(bromomethyl)benzoyl bromide

There total 1 articles about 3-(bromomethyl)benzoyl bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-Methylbenzoyl chloride (1711-06-4) → 3-(bromomethyl)benzoyl bromide (209743-33-9)

Guidance literature:

With bromine; at 185 - 195 ℃;

Reference yield: 90.0%

tert-butyl 3-[(propan-2-ylamino)methyl]benzoate (1326778-90-8) + 3-(bromomethyl)benzoyl bromide (209743-33-9) + isopropylamine (75-31-0) → C26H36N2O3 (1326778-91-9)

Guidance literature:

tert-butyl 3-[(propan-2-ylamino)methyl]benzoate; 3-(bromomethyl)benzoyl bromide; With triethylamine; In tetrahydrofuran; at 0 ℃; for 1h; Inert atmosphere;

isopropylamine; With triethylamine; In tetrahydrofuran; at 20 ℃; Inert atmosphere;

DOI:10.1002/ejoc.201100232

Reference yield: 87.0%

C24H32N2O3 (1326778-94-2) + 3-(bromomethyl)benzoyl bromide (209743-33-9) + ethylamine (75-04-7,85404-22-4) → C34H43N3O4 (1326778-95-3)

Guidance literature:

C₂₄H₃₂N₂O₃; 3-(bromomethyl)benzoyl bromide; With triethylamine; In tetrahydrofuran; at 0 ℃; for 1h; Inert atmosphere;

ethylamine; With triethylamine; In tetrahydrofuran; at 20 ℃; Inert atmosphere;

DOI:10.1002/ejoc.201100232

upstream raw materials:

3-Methylbenzoyl chloride

Downstream raw materials:

ethyl 3-bromomethylbenzoate

3-bromomethylbenzoic acid

(3-(bromomethyl)phenyl)(piperidin-1-yl)methanone

C₃₇H₄₉N₃O₄