L-GLUTAMINE METHYL ESTER HYDROCHLORIDE

Base Information

• Chemical Name: L-GLUTAMINE METHYL ESTER HYDROCHLORIDE
• CAS No.: 32668-14-7
• Molecular Formula: C₆H₁₂N₂O₃*ClH
• Molecular Weight: 196.634
• Hs Code.: 2924199090
• Mol file: 32668-14-7.mol

Synonyms:Glutamine,methyl ester, monohydrochloride, L- (8CI);L-Glutamine, methyl ester,monohydrochloride (9CI);L-Glutamine methyl ester hydrochloride;

Chemical Property of L-GLUTAMINE METHYL ESTER HYDROCHLORIDE

Chemical Property:

• Vapor Pressure: 7.86E-06mmHg at 25°C
• Boiling Point: 369.9 °C at 760mmHg
• Flash Point: 177.5 °C
• PSA: 95.41000
• LogP: 0.95480
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

L-Glutamine Methyl Ester Hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Uses: L-Glutamine Methyl Ester is protected L-Glutamine (G597000). L-Glutamine is an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture. L-Glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however, L-glutamine degrades relatively rapidly. Optimal cell performance usually requires supplementation of the media with L-glutamine prior to use.

Technology Process of L-GLUTAMINE METHYL ESTER HYDROCHLORIDE

There total 3 articles about L-GLUTAMINE METHYL ESTER HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

→ L-glutamine methyl ester monohydrochloride (32668-14-7,56159-65-0,74817-54-2)

Guidance literature:

Reference yield:

methanol (67-56-1) + L-glutamine (56-85-9,26700-71-0) → L-glutamine methyl ester monohydrochloride (32668-14-7,56159-65-0,74817-54-2)

Guidance literature:

With thionyl chloride; at 60 - 70 ℃;

Reference yield:

N2-benzyloxycarbonyl-L-glutamine methyl ester (13907-82-9,2650-67-1) → L-glutamine methyl ester monohydrochloride (32668-14-7,56159-65-0,74817-54-2)

Guidance literature:

With hydrogenchloride; palladium; Hydrogenation;

DOI:10.1021/ja01639a063

upstream raw materials:

N²-benzyloxycarbonyl-L-glutamine methyl ester

methanol

L-glutamine

Downstream raw materials:

(S)-2-[((S)-2-{(S)-2-[Benzyloxycarbonyl-((R)-2-tert-butoxycarbonylamino-3-tritylsulfanyl-propyl)-amino]-3-methyl-butyryl}-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl)-amino]-4-carbamoyl-butyric acid methyl ester

4-carbamoyl-2-(2-nitrobenzylamino)butyric acid methyl ester

methyl 2-amino-5-[2-(3-benzoylphenyl)propanamido]-5-oxopentanoate

N-L-Glutaminyl-γ-aminobuttersaeureethylester

Refernces

• 1、 Dubey,Jain,Bhadoria,Sinha. "Synthesis, characterization and pharmacological evaluation of amino acid conjugates of ketoprofen". experimental part. p. 1170 - 1174. Retrieved 2012/08/28.