3-AMINO-6-CHLORO-5-DIMETHYLAMINO-N-2-PYRIDINYLPYRAZINECARBOXAMIDE HYDROCHLORIDE

Base Information

• Chemical Name: 3-AMINO-6-CHLORO-5-DIMETHYLAMINO-N-2-PYRIDINYLPYRAZINECARBOXAMIDE HYDROCHLORIDE
• CAS No.: 37804-11-8
• Molecular Formula: C₁₂H₁₃ClN₆O
• Molecular Weight: 292.728
• Mol file: 37804-11-8.mol

Synonyms:Pyrazinecarboxamide,3-amino-6-chloro-5-(dimethylamino)-N-2-pyridinyl- (9CI)

Chemical Property of 3-AMINO-6-CHLORO-5-DIMETHYLAMINO-N-2-PYRIDINYLPYRAZINECARBOXAMIDE HYDROCHLORIDE

Chemical Property:

• Vapor Pressure: 2.29E-09mmHg at 25°C
• Boiling Point: 473.6°C at 760 mmHg
• Flash Point: 240.3°C
• PSA: 97.03000
• LogP: 2.88170
• Storage Temp.: Desiccate at RT

Purity/Quality:

98%Min ^*data from raw suppliers

ACDPP hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-AMINO-6-CHLORO-5-DIMETHYLAMINO-N-2-PYRIDINYLPYRAZINECARBOXAMIDE HYDROCHLORIDE

There total 2 articles about 3-AMINO-6-CHLORO-5-DIMETHYLAMINO-N-2-PYRIDINYLPYRAZINECARBOXAMIDE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-aminopyridine (504-29-0) + 3-amino-6-chloro-5-dimethylamino-pyrazine-2-carboxylic acid (27245-43-8) → 3-amino-6-chloro-5-(dimethylamino)-N-pyridin-2-yl-pyrazine-2-carboxamide (37804-11-8)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In dichloromethane; at 20 ℃; for 18h;

DOI:10.1016/j.bmcl.2004.11.078

Reference yield:

→ 3-amino-6-chloro-5-(dimethylamino)-N-pyridin-2-yl-pyrazine-2-carboxamide (37804-11-8)

Guidance literature:

upstream raw materials:

2-aminopyridine

3-amino-6-chloro-5-dimethylamino-pyrazine-2-carboxylic acid

Refernces

• 1、 -. "BIPYRIDYL AMIDES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR-5". Page/Page column 47. . Retrieved 2008/06/13.