L-BUTHIONINE

Base Information

• Chemical Name: L-BUTHIONINE
• CAS No.: 13073-21-7
• Molecular Formula: C₈H₁₇NO₂S
• Molecular Weight: 191.294
• Hs Code.: 2930909090
• Mol file: 13073-21-7.mol

Synonyms:Butyricacid, 2-amino-4-(butylthio)-, L- (8CI);S-Butyl-L-homocysteine;L-2-Amino-4-(butylthio)butyric Acid;

Chemical Property of L-BUTHIONINE

Chemical Property:

• Appearance/Colour: White solid
• Vapor Pressure: 2.22E-05mmHg at 25°C
• Melting Point: 266-268 °C
• Refractive Index: 1.514
• Boiling Point: 335.7 °C at 760 mmHg
• Flash Point: 156.8 °C
• PSA: 88.62000
• Density: 1.104 g/cm³
• LogP: 2.02200
• Storage Temp.: -20°C Freezer
• Solubility.: Aqueous Acid (Slightly), Aqueous Base (Slightly)

Purity/Quality:

98%Min ^*data from raw suppliers

L-Buthionine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (S)-Homocysteine thioether

Technology Process of L-BUTHIONINE

There total 7 articles about L-BUTHIONINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1-bromo-butane (109-65-9) + L-homocystine (626-72-2,870-93-9,6027-15-2,7093-69-8,462-10-2) → S-butyl-L-homocysteine (13073-21-7,13073-22-8,3343-64-4)

Guidance literature:

With ammonia; sodium; at -78 ℃;

DOI:10.1002/anie.201308272

Reference yield: 99.0%

→ S-butyl-L-homocysteine (13073-21-7,13073-22-8,3343-64-4)

Guidance literature:

With ammonia; sodium; for 0.0166667h;

Reference yield:

C13H25NO4S (1396969-20-2) → S-butyl-L-homocysteine (13073-21-7,13073-22-8,3343-64-4)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 15h;

DOI:10.1039/c4cc08478k

upstream raw materials:

S-benzyl-L-homocysteine

1-bromo-butane

L-homocystine

S-butyl-D,L-homocysteine

Downstream raw materials:

S-butyl-5'-thio-adenosine

buthionine sulfoxide

Refernces

• 1、 Dippe,Brandt,Rost,Porzel,Schmidt,Wessjohann. "Rationally engineered variants of S-adenosylmethionine (SAM) synthase: Reduced product inhibition and synthesis of artificial cofactor homologues". . p. 3637 - 3640. Retrieved 2015/03/30.