Folinic acid calcium salt pentahydrate

Base Information

• Chemical Name: Folinic acid calcium salt pentahydrate
• CAS No.: 41927-89-3
• Molecular Formula: C20H31CaN7O12
• Molecular Weight: 601.58
• Mol file: 41927-89-3.mol

Synonyms:Leucovorin pentahydrate;

Chemical Property of Folinic acid calcium salt pentahydrate

Chemical Property:

• Melting Point: 240-250 °C
• PSA: 244.25000
• LogP: 1.08950
• Storage Temp.: 0-6°C
• Solubility.: Aqueous (Slightly, Sonicated), Water (Sparingly, Heated, Sonicated)

Purity/Quality:

99% ^*data from raw suppliers

Leucovorin Calcium Salt Pentahydrate ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

Useful:

• Uses: Anti-anemic (folate deficiency); antidote (to folic acid antagonists).
• Clinical Use: Folinic acid rescue Enhancement of 5-fluorouracil cytotoxicity in advanced colorectal cancer Folate deficiency
• Drug interactions: Potentially hazardous interactions with other drugs Should not be administered simultaneously with a folic acid antagonist as this may nullify the effect of the antagonist. Cytotoxics: avoid with panitumumab and raltitrexed.