DIMETHYL CARBONATE-D6

Base Information

• Chemical Name: DIMETHYL CARBONATE-D6
• CAS No.: 108481-44-3
• Molecular Formula: C₃H₆O₃
• Molecular Weight: 96.0312
• Hs Code.: 28459000
• Mol file: 108481-44-3.mol

Synonyms:DIMETHYL CARBONATE-D6;DIMETHYL-D6 CARBONATE

Chemical Property of DIMETHYL CARBONATE-D6

Chemical Property:

• Flash Point: 16℃
• PSA: 35.53000
• LogP: 0.39920

Purity/Quality:

99% ^*data from raw suppliers

Dimethyl-d6 Carbonate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F
• Hazard Codes: F
• Statements: 11
• Safety Statements: 9-16-2017/9/16

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DIMETHYL CARBONATE-D6

There total 2 articles about DIMETHYL CARBONATE-D6 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + 1,1,1-trideuteromethanol (1849-29-2) + carbon monoxide (201230-82-2) → [2H6]dimethyl carbonate (108481-44-3) + [2H6]dimethyl carbonate

Guidance literature:

With oxygen-covered gold⁽¹¹¹⁾; at -123.16 - 26.84 ℃;

DOI:10.1021/ja207389z

Reference yield:

Trideutero-methylbromid (1111-88-2) → [2H6]dimethyl carbonate (108481-44-3)

Guidance literature:

DOI:10.1139/v56-022

Reference yield: 48.0%

[2H6]dimethyl carbonate (108481-44-3) + ethyl 3-iodo-4-methoxybenzoate (207115-38-6) → C12H9(2)H7O3 + C12H10(2)H6O3 + C12H7(2)H9O3

Guidance literature:

ethyl 3-iodo-4-methoxybenzoate; With tetrabutylammomium bromide; potassium carbonate; palladium dichloride; In N,N-dimethyl acetamide; Schlenk technique; Inert atmosphere;

[²H₆]dimethyl carbonate; In N,N-dimethyl acetamide; at 105 ℃; for 12h; Overall yield = 34.5 mg; regioselective reaction; Schlenk technique; Inert atmosphere;

DOI:10.1021/jacs.0c13057

upstream raw materials:

Trideutero-methylbromid

methanol

1,1,1-trideuteromethanol

carbon monoxide

Refernces

• 1、 Xu, Bingjun,Madix, Robert J.,Friend, Cynthia M.. "Activated metallic gold as an agent for direct methoxycarbonylation". supporting information; experimental part. p. 20378 - 20383. Retrieved 2012/02/06.