Carbazole-9-carbonyl Chloride

Base Information

• Chemical Name: Carbazole-9-carbonyl Chloride
• CAS No.: 73500-82-0
• Molecular Formula: C13H8ClNO
• Molecular Weight: 229.666
• Hs Code.: 2933990090
• European Community (EC) Number: 621-064-1
• DSSTox Substance ID: DTXSID60390777
• Nikkaji Number: J208.244F
• Wikidata: Q82187797
• Mol file: 73500-82-0.mol

Synonyms:73500-82-0;Carbazole-9-carbonyl Chloride;9-(Chloroformyl)carbazole;Carbazole-N-carbonyl Chloride;9H-Carbazole-9-carbonyl chloride;9-(Chlorocarbonyl)carbazole;SCHEMBL592694;9-(Chloroformyl)-9H-carbazole;DTXSID60390777;RCENRFKQKSIRLA-UHFFFAOYSA-N;MFCD00059689;AKOS015840948;FT-0641467;T71281;EN300-7414075;A837843

Chemical Property of Carbazole-9-carbonyl Chloride

Chemical Property:

• Appearance/Colour: Light red powder
• Vapor Pressure: 7.54E-07mmHg at 25°C
• Melting Point: 100-104 °C
• Refractive Index: 1.661
• Boiling Point: 407.5 °C at 760 mmHg
• Flash Point: 200.2 °C
• PSA: 22.00000
• Density: 1.32 g/cm³
• LogP: 4.00140
• Storage Temp.: 2-8°C
• XLogP3: 4.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 229.0294416
• Heavy Atom Count: 16
• Complexity: 272

Purity/Quality:

98%,99%, ^*data from raw suppliers

Carbazole-9-carbonyl Chloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C3=CC=CC=C3N2C(=O)Cl

Technology Process of Carbazole-9-carbonyl Chloride

There total 2 articles about Carbazole-9-carbonyl Chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phosgene (75-44-5) + 9H-carbazole (86-74-8,105184-46-1,97960-57-1) → 9-carbazole carbonyl chloride (73500-82-0)

Guidance literature:

With pyridine; In toluene; at 90 ℃; for 0.166667h;

DOI:10.1016/S0040-4039(00)88831-0

Reference yield:

bis(trichloromethyl) carbonate (32315-10-9) + 9H-carbazole (86-74-8,105184-46-1,97960-57-1) → 9-carbazole carbonyl chloride (73500-82-0)

Guidance literature:

In tetrahydrofuran; ethyl acetate; at 0 - 80 ℃; for 5.5h;

DOI:10.1016/j.reactfunctpolym.2009.11.001

Reference yield: 92.0%

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + 9-carbazole carbonyl chloride (73500-82-0) → 4-nitrophenyl 9H-carbazole-9-carboxylate (135462-32-7)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 3.5h;

upstream raw materials:

phosgene

9H-carbazole

bis(trichloromethyl) carbonate

Downstream raw materials:

(9H-carbazol-9-yl)(2-chlorophenyl)methanone

4-nitrophenyl 9H-carbazole-9-carboxylate

(S)-N-(1-(2-(4-fluorophenyl)ethyl)pyrrolidin-3-yl)carbazole-9-carboxamide

Refernces

• 1、 Luo, Xiaofeng,Chang, Jie,Deng, Jianping,Yang, Wantai. "Synthesis and characterization of poly(N-propargylurea)s with helical conformation, optical activity and fluorescence properties". . p. 116 - 121. Retrieved 2010.