9Z,12Z-OCTADECADIENOIC-9,10,12,13-D4 ACID

Base Information

• Chemical Name: 9Z,12Z-OCTADECADIENOIC-9,10,12,13-D4 ACID
• CAS No.: 79050-23-0
• Molecular Formula: C18H28 D4 O2
• Molecular Weight: 284.419
• Mol file: 79050-23-0.mol

Synonyms:9,12-Octadecadienoic-9,10,12,13-d4acid, (Z,Z)-

Chemical Property of 9Z,12Z-OCTADECADIENOIC-9,10,12,13-D4 ACID

Chemical Property:

• PSA: 37.30000
• LogP: 5.88450

Purity/Quality:

99% ^*data from raw suppliers

LinoleicAcid-d4 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Linoleic acid-d4 contains four deuterium atoms at the 9, 10, 12, and 13 positions. It is intended for use as an internal standard for the quantification of linoleic acid by GC- or LC-mass spectrometry. Linoleic acid is a PUFA found in plant tissues and most cooking oils. Deficiencies in the essential fatty acid linoleic acid are linked to coronary heart disease, growth retardation, and allergies. Linoleic acid can be metabolized by prostaglandin H synthases (PGHS) to form 9- and 13-HODE. The Km is 12 μM for human PGHS-1 and 27 μM for PGHS-2.[Cayman Chemical] Linoleic Acid-d4 is a labeled activator of PPAR.

Technology Process of 9Z,12Z-OCTADECADIENOIC-9,10,12,13-D4 ACID

There total 1 articles about 9Z,12Z-OCTADECADIENOIC-9,10,12,13-D4 ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl octadec-9,12-diynoic acid (62439-44-5) → linoleic acid (60-33-3,116745-32-5,26085-09-6,64080-88-2,7049-66-3,949900-18-9,60476-23-5,6144-28-1,67922-65-0,89718-18-3) + [9,10,12,13-2H]-(Z,Z)-9,12-octadecadienoic acid (79050-23-0)

Guidance literature:

methyl octadec-9,12-diynoic acid; With benzo[1,3,2]dioxaborole; at 60 ℃; for 5h;

With deuteroacetic acid; acetic acid; for 5h; Heating;

With potassium hydroxide; In water; for 1h; Further stages. Title compound not separated from byproducts.; Heating;

DOI:10.1016/j.tetlet.2008.04.023

upstream raw materials:

methyl octadec-9,12-diynoic acid

Refernces