(5R,11R)-5,11-DIETHYL-5,6,11,12-TETRAHYDRO-2,8-CHRYSENEDIOL

Base Information

• Chemical Name: (5R,11R)-5,11-DIETHYL-5,6,11,12-TETRAHYDRO-2,8-CHRYSENEDIOL
• CAS No.: 138090-06-9
• Molecular Formula: C₂₂H₂₄O₂
• Molecular Weight: 320.431
• Mol file: 138090-06-9.mol

Synonyms:2,8-Chrysenediol,5,11-diethyl-5,6,11,12-tetrahydro-, cis-; 5,11-cis-Diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol

Chemical Property of (5R,11R)-5,11-DIETHYL-5,6,11,12-TETRAHYDRO-2,8-CHRYSENEDIOL

Chemical Property:

• Vapor Pressure: 2.17E-11mmHg at 25°C
• Boiling Point: 519°Cat760mmHg
• Flash Point: 239.5°C
• PSA: 40.46000
• Density: 1.21g/cm³
• LogP: 5.17320
• Storage Temp.: 2-8°C
• Solubility.: DMSO: 20 mg/mL

Purity/Quality:

99%min ^*data from raw suppliers

cis-5,11-Diethyl-5,6,11,12-tetrahydro-2,8-chrysenediol ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Uses: cis-5,11-Diethyl-5,6,11,12-tetrahydro-2,8-chrysenediol is a fluorescent ligands for the estrogen receptor. A series of tetrahydrochrysenes were prepared as fluorescent ligands for the estrogen receptor. cis-5,11-Diethyl-5,6,11,12-tetrahydro-2,8-chrysenediol is a fluorescent and selective ligand that can be used to investigate the interactions between ligand and receptor of estrogen receptors (ERs) (1,2,3). cis-5,11-Diethyl-5,6,11,12-tetrahydro-2,8-chrysenediol is an ERα agonist and an ERβ antagonist.

Technology Process of (5R,11R)-5,11-DIETHYL-5,6,11,12-TETRAHYDRO-2,8-CHRYSENEDIOL

There total 1 articles about (5R,11R)-5,11-DIETHYL-5,6,11,12-TETRAHYDRO-2,8-CHRYSENEDIOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,8-dimethoxy-5,11-cis-diethyl-5,6,11,12-tetrahydrochrysene (138090-05-8) → 5,11-cis-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol (138090-06-9,221368-54-3)

Guidance literature:

With boron tribromide; In dichloromethane; for 16h; Yield given; Ambient temperature;

DOI:10.1021/jo00030a039

upstream raw materials:

2,8-dimethoxy-5,11-cis-diethyl-5,6,11,12-tetrahydrochrysene

Refernces