2-Chloro-1-(2-chloroethoxy)-1,1,2-trifluoroethane

Base Information

• Chemical Name: 2-Chloro-1-(2-chloroethoxy)-1,1,2-trifluoroethane
• CAS No.: 380-45-0
• Molecular Formula: C₄H₅Cl₂F₃O
• Molecular Weight: 196.984
• Hs Code.: 2909199090
• DSSTox Substance ID: DTXSID00371383
• Mol file: 380-45-0.mol

Synonyms:2-chloro-1-(2-chloroethoxy)-1,1,2-trifluoroethane;380-45-0;2-Chloroethyl 2-chloro-1,1,2-trifluoroethyl ether;MFCD00153738;DTXSID00371383;AKOS006230466

Chemical Property of 2-Chloro-1-(2-chloroethoxy)-1,1,2-trifluoroethane

Chemical Property:

• Vapor Pressure: 4.57mmHg at 25°C
• Boiling Point: 152°Cat760mmHg
• Flash Point: 45.7°C
• PSA: 9.23000
• Density: 1.402g/cm³
• LogP: 2.36900
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 195.9669547
• Heavy Atom Count: 10
• Complexity: 101

Purity/Quality:

98%Min ^*data from raw suppliers

2-CHLORO-1-(2-CHLOROETHOXY)-1,1,2-TRIFLUOROETHANE 95.00% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CCl)OC(C(F)Cl)(F)F

Technology Process of 2-Chloro-1-(2-chloroethoxy)-1,1,2-trifluoroethane

There total 3 articles about 2-Chloro-1-(2-chloroethoxy)-1,1,2-trifluoroethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(2-chloro-1,1,2-trifluoro-ethoxy)-ethanol (380-47-2) → (2-chloro-ethyl)-(2-chloro-1,1,2-trifluoro-ethyl)-ether (380-45-0)

Guidance literature:

With chloroform; phosphorus pentachloride;

DOI:10.1021/ja01129a036

Reference yield:

ethoxyflurane (310-71-4) → (1-chloro-ethyl)-(2-chloro-1,1,2-trifluoro-ethyl)-ether (562-64-1) + (2-chloro-ethyl)-(2-chloro-1,1,2-trifluoro-ethyl)-ether (380-45-0)

Guidance literature:

With chlorine; Belichtung;

DOI:10.1021/ja01129a036 DOI:10.1021/ja01634a073 DOI:10.1021/ja01123a048

Reference yield:

ethoxyflurane (310-71-4) → (1-chloro-ethyl)-(2-chloro-1,1,2-trifluoro-ethyl)-ether (562-64-1) + (2-chloro-ethyl)-(2-chloro-1,1,2-trifluoro-ethyl)-ether (380-45-0) + (2-chloro-1,1,2-trifluoro-ethyl)-(1,2,2-trichloro-ethyl)-ether (406-65-5)

Guidance literature:

Photochlorierung in fluessiger Phase;

DOI:10.1021/ja01129a036 DOI:10.1021/ja01123a048

upstream raw materials:

ethoxyflurane

2-(2-chloro-1,1,2-trifluoro-ethoxy)-ethanol