C₂₇H₂₄ClFN₄O₆

Base Information

• Chemical Name: C₂₇H₂₄ClFN₄O₆
• CAS No.: 1622396-73-9
• Molecular Formula: C₂₇H₂₄ClFN₄O₆
• Molecular Weight: 554.962
• Mol file: 1622396-73-9.mol

Synonyms:C₂₇H₂₄ClFN₄O₆

Chemical Property of C₂₇H₂₄ClFN₄O₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₇H₂₄ClFN₄O₆

There total 14 articles about C₂₇H₂₄ClFN₄O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C29H28ClFN4O6 (1622396-72-8) → C27H24ClFN4O6 (1622396-73-9)

Guidance literature:

With water; lithium hydroxide; In tetrahydrofuran; at 20 ℃;

Reference yield:

2-fluoro-5-methyl-phenylisocyanate → C27H24ClFN4O6 (1622396-73-9)

Guidance literature:

Multi-step reaction with 2 steps

1: toluene / 3 h / 70 °C

2: lithium hydroxide; water / tetrahydrofuran / 20 °C

With water; lithium hydroxide; In tetrahydrofuran; toluene;

Reference yield:

4-hydroxy-3-methoxybenzoic acid methyl ester (3943-74-6) → C27H24ClFN4O6 (1622396-73-9)

Guidance literature:

Multi-step reaction with 12 steps

1: potassium carbonate / N,N-dimethyl-formamide / 3 h / 100 °C

2: nitric acid; acetic acid / 0.33 h / -10 °C

3: iron; ammonium chloride / water; methanol / 105 °C

4: ammonium acetate; methanol / 100 °C

5: methanesulfonic acid; trifluoroacetic acid / 3 h / Reflux

6: pyridine / 3 h / 120 °C

7: thionyl chloride / N,N-dimethyl-formamide / 1.5 h / Reflux

8: methanol; ammonia / dichloromethane / 0.17 h / 80 °C

9: potassium carbonate / tetrahydrofuran / 20 °C

10: caesium carbonate / acetonitrile / 2 h / 50 °C

11: toluene / 3 h / 70 °C

12: lithium hydroxide; water / tetrahydrofuran / 20 °C

With pyridine; methanol; thionyl chloride; methanesulfonic acid; ammonium acetate; ammonia; water; nitric acid; iron; potassium carbonate; ammonium chloride; caesium carbonate; acetic acid; trifluoroacetic acid; lithium hydroxide; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; toluene; acetonitrile;

upstream raw materials:

4-hydroxy-3-methoxybenzoic acid methyl ester

methyl 4-(benzyloxy)-3-methoxybenzoate

methyl 4-(benzyloxy)-5-methoxy-2-nitrobenzoate

methyl 2-amino-4-(benzyloxy)-5-methoxybenzoate

Downstream raw materials:

C₃₄H₃₅ClFN₅O₆

Refernces