1-PHENYL-1H-BENZOIMIDAZOLE

Base Information

• Chemical Name: 1-PHENYL-1H-BENZOIMIDAZOLE
• CAS No.: 2622-60-8
• Molecular Formula: C13H10N2
• Molecular Weight: 194.236
• Mol file: 2622-60-8.mol

Synonyms:Benzimidazole,1-phenyl- (6CI,7CI,8CI);1-Phenyl-1H-benzimidazole;1-Phenylbenzimidazole;N-Phenylbenzimidazole;

Chemical Property of 1-PHENYL-1H-BENZOIMIDAZOLE

Chemical Property:

• Vapor Pressure: 1.86E-05mmHg at 25°C
• Melting Point: 98℃
• Refractive Index: 1.638
• Boiling Point: 363 °C at 760 mmHg
• PKA: 4.42±0.10(Predicted)
• Flash Point: 173.3 °C
• PSA: 17.82000
• Density: 1.13 g/cm³
• LogP: 3.02550
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99.3% ^*data from raw suppliers

1-phenyl-1h-benzo[d]imidazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 1-phenyl-1h-benzo[d]imidazole is a useful research chemical.

Technology Process of 1-PHENYL-1H-BENZOIMIDAZOLE

There total 57 articles about 1-PHENYL-1H-BENZOIMIDAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

benzoimidazole (51-17-2,79351-71-6) + phenylboronic acid (98-80-6) → 1-phenyl-1H-benzoimidazole (2622-60-8)

Guidance literature:

With N,N,N,N,-tetramethylethylenediamine; oxygen; copper(II) nitrate; In methanol; at 20 ℃; for 24h; under 760.051 Torr;

DOI:10.1002/adsc.200800730

Reference yield: 99.0%

benzoimidazole (51-17-2,79351-71-6) + bromobenzene (108-86-1,52753-63-6) → 1-phenyl-1H-benzoimidazole (2622-60-8)

Guidance literature:

With copper(l) iodide; potassium carbonate; heptakis(6-amino-6-deoxy)-β-cyclodextrin; In dimethyl sulfoxide; at 110 ℃; for 24h; Sealed tube;

DOI:10.1021/jo801811w

Reference yield: 99.0%

benzoimidazole (51-17-2,79351-71-6) + iodobenzene (591-50-4) → 1-phenyl-1H-benzoimidazole (2622-60-8)

Guidance literature:

With copper(l) iodide; potassium carbonate; L-proline; PS[DMVBIM][Pro]; In dimethyl sulfoxide; at 120 ℃; for 60h;

DOI:10.1021/ja073633n

upstream raw materials:

formic acid

N-phenyl-1,2-benzenediamine

3-phenyl-2-(phenylimino)-5-(phenylmethylidene)-1,3-thiazolidin-4-one

3-methyl-10-phenylisolloxazine

Downstream raw materials:

1,1'-diphenyl-1H,1'H-2,2'-bibenzo[d]imidazole

1,1'-dibenzyl-1H,1'H-2,2'-bibenzo[d]imidazole

1-benzyl-1'-phenyl-1H,1'H-2,2'-bibenzo[d]imidazole

Br^(1-)*C₂₉H₂₃N₂O⁽¹⁺⁾

Refernces

• 1、 Sireci, Nihat,Yilmaz, Uelkue,Kuecuekbay, Hasan,Akkurt, Mehmet,Baktir, Zeliha,Tuerktekin, Sevim,Bueykgngoer, Orhan. "Synthesis of 1-substituted benzimidazole metal complexes and structural characterization of dichlorobis(1-phenyl- 1H-benzimidazole-kN 3)cobalt(II) and dichlorobis (1-phenyl-1H-benzimidazole-kN 3)zinc(II)". . p. 1894 - 1902. Retrieved 2011.
• 2、 Li, Cheng-An,Ji, Wei,Qu, Jian,Jing, Su,Gao, Fei,Zhu, Dun-Ru. "A PEG/copper(i) halide cluster as an eco-friendly catalytic system for C-N bond formation". . p. 7463 - 7470. Retrieved 2018.
• 3、 An, Jie,Lai, Zemin,Li, Hengzhao,Peng, Mengqi,Sun, Yanhao,Yan, Zihan,Yang, Ruoyan,Zhang, Yuntong. "Methanol as the C1source: Redox coupling of nitrobenzenes and alcohols for the synthesis of benzimidazoles". supporting information. p. 748 - 753. Retrieved 2022/02/02.
• 4、 Zhang, Chenlu,Zhu, Hai,Gang, Kaiyue,Tao, Minli,Ma, Ning,Zhang, Wenqin. "Immobilization of copper(II) into polyacrylonitrile fiber toward efficient and recyclable catalyst in Chan-Lam coupling reactions". . . Retrieved 2021/02/09.