6-PHENYL-2,3-DIHYDROIMIDAZO[2,1-B][1,3]THIAZOLE

Base Information

• Chemical Name: 6-PHENYL-2,3-DIHYDROIMIDAZO[2,1-B][1,3]THIAZOLE
• CAS No.: 4335-28-8
• Molecular Formula: C11H10 N2 S
• Molecular Weight: 202.28
• Hs Code.: 2934100090
• Mol file: 4335-28-8.mol

Synonyms:6-Phenyl-2,3-dihydroimidazo[2,1-b]thiazole

Chemical Property of 6-PHENYL-2,3-DIHYDROIMIDAZO[2,1-B][1,3]THIAZOLE

Chemical Property:

• Melting Point: 147oC
• PSA: 43.12000
• LogP: 2.65580

Purity/Quality:

99%, ^*data from raw suppliers

2, 3-Dihydro-6-phenyl-imidazo[2, 1-b]thiazole Hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 6-Phenyl-2,3-dihydroimidazo[2,1-b]thiazole is a degradation product of levamisole. Levamisole is an anthelmintic.

Technology Process of 6-PHENYL-2,3-DIHYDROIMIDAZO[2,1-B][1,3]THIAZOLE

There total 4 articles about 6-PHENYL-2,3-DIHYDROIMIDAZO[2,1-B][1,3]THIAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

4,5-Dihydro-thiazol-2-ylamin (1779-81-3) → 2,3-diidro-6-fenilimidazo<2,1-b>tiazolo (4335-28-8)

Guidance literature:

In ethanol; for 1h; Heating;

DOI:10.1021/jo00253a012

Reference yield:

2-(2-imino-thiazolidin-3-yl)-1-phenyl-ethanone; hydrobromide (4335-26-6) → 2,3-diidro-6-fenilimidazo<2,1-b>tiazolo (4335-28-8)

Guidance literature:

With sodium hydroxide; Heating;

Reference yield:

4,5-Dihydro-thiazol-2-ylamin (1779-81-3) + α-bromoacetophenone (70-11-1) → 2,3-diidro-6-fenilimidazo<2,1-b>tiazolo (4335-28-8)

Guidance literature:

In ethanol; Heating;

DOI:10.1007/BF00832994

upstream raw materials:

4,5-Dihydro-thiazol-2-ylamin

α-bromoacetophenone

2-(2-imino-thiazolidin-3-yl)-1-phenyl-ethanone; hydrobromide

Downstream raw materials:

5-<1-(ethoxycarbonyl)-1,4-dihydro-4-pyridyl>-6-phenylimidazo<2,1-b>thiazoline

2-butylmercapto-4-phenyl-1⁽³⁾H-imidazole

2-(methylthio)-4-phenyl-1H-imidazole

4-phenyl-2-thioxo-1-vinyl-4-imidazoline

Refernces