2,5-DIMETHOXYTEREPHTHALALDEHYDE

Base Information

• Chemical Name: 2,5-DIMETHOXYTEREPHTHALALDEHYDE
• CAS No.: 7310-97-6
• Molecular Formula: C10H10O4
• Molecular Weight: 194.187
• Hs Code.: 2912490090
• Mol file: 7310-97-6.mol

Synonyms:Terephthalaldehyde, 2,5-dimethoxy- (7CI,8CI);2,5-Dimethoxy-1,4-benzenedicarboxaldehyde;2,5-Dimethoxyterephthalaldehyde;2,5-dimethoxybenzene-1,4-dicarbaldehyde;1,4-benzenedicarboxaldehyde, 2,5-dimethoxy-;2,5-dimethoxyterephthalaldehyde;

Chemical Property of 2,5-DIMETHOXYTEREPHTHALALDEHYDE

Chemical Property:

• Vapor Pressure: 1.04E-05mmHg at 25°C
• Melting Point: 220℃
• Refractive Index: 1.574
• Boiling Point: 371.4 °C at 760 mmHg
• Flash Point: 168.2 °C
• PSA: 52.60000
• Density: 1.207 g/cm³
• LogP: 1.32880
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

98%, ^*data from raw suppliers

2,5-dimethoxyterephthalaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 1. Synthesis of bis(N-salicylidene-aniline)s BSANs 2. COF applications

Technology Process of 2,5-DIMETHOXYTEREPHTHALALDEHYDE

There total 24 articles about 2,5-DIMETHOXYTEREPHTHALALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1,4-bis(bromomethyl)-2,5-dimethoxybenzene (50874-27-6) → 2,5-dimethoxyterephthalaldehyde (7310-97-6)

Guidance literature:

With dipotassium hydrogenphosphate; Potassium benzeneselenite; In acetonitrile; for 16h;

DOI:10.1055/s-1984-30956

Reference yield: 92.0%

N,N-dimethyl-formamide (68-12-2,33513-42-7) + 1,4-dimethoxybezene (150-78-7) → 2,5-dimethoxyterephthalaldehyde (7310-97-6)

Guidance literature:

1,4-dimethoxybezene; With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In diethyl ether; hexane; at -78 ℃; for 2h;

N,N-dimethyl-formamide; In tetrahydrofuran; diethyl ether; hexane; at 20 ℃; for 0.5h; Further stages.;

DOI:10.1039/b212102f

Reference yield: 82.0%

1,4-bis(chloromethyl)-2,5-dimethoxybenzene (3752-97-4) → 2,5-dimethoxyterephthalaldehyde (7310-97-6)

Guidance literature:

1,4-bis(chloromethyl)-2,5-dimethoxybenzene; With hexamethylenetetramine; In chloroform; for 16h; Reflux;

With formaldehyd; water; for 21h; Reflux;

DOI:10.5012/bkcs.2010.31.10.2755

upstream raw materials:

1,4-bis(chloromethyl)-2,5-dimethoxybenzene

2,5-dihydroxyterephthaldeyde

dimethyl sulfate

1,4-dihydroxymethyl-2,5-dimethoxybenzaldehyde

Downstream raw materials:

1,4-bis-(α-hydroxy-4-methoxy-phenethyl)-2,5-dimethoxy-benzene

1,4-bis-(α-hydroxy-phenethyl)-2,5-dimethoxy-benzene

2,5-dihydroxyterephthaldeyde

2,5-dimethoxyterephthalic acid

Refernces

• 1、 Chen, Hongli,Chen, Xingguo,Lv, Wenjuan,Pan, Congjie,Wang, Guoxiu. "Synthesis of a novel chiral DA-TD covalent organic framework for open-tubular capillary electrochromatography enantioseparation". supporting information. p. 403 - 406. Retrieved 2022/01/19.
• 2、 Chen, Zhuang-Zhuang,Deng, Yun-Hu,Zhang, Ting,Dong, Wen-Kui. "A novel bifunctional-group salamo-like multi-purpose dye probe based on ESIPT and RAHB effect: Distinction of cyanide and hydrazine through optical signal differential protocol". supporting information. . Retrieved 2021/06/29.