PYRIDINE-3-SULFONYL CHLORIDE

Base Information

• Chemical Name: PYRIDINE-3-SULFONYL CHLORIDE
• CAS No.: 42899-76-3
• Molecular Formula: C5H4ClNO2S.ClH
• Molecular Weight: 214.072
• Hs Code.: 29333990
• Mol file: 42899-76-3.mol

Synonyms:3-Pyridinesulfonylchloride, hydrochloride (9CI);3-Pyridylsulfonyl chloride hydrochloride;

Chemical Property of PYRIDINE-3-SULFONYL CHLORIDE

Chemical Property:

• Melting Point: 120-126°C
• Boiling Point: 314.4 °C at 760 mmHg
• Flash Point: 143.9 °C
• PSA: 55.41000
• LogP: 2.08990
• Storage Temp.: Store below -20C
• Sensitive.: Moisture Sensitive
• Water Solubility.: Reacts with water.

Purity/Quality:

99% ^*data from raw suppliers

Pyridine-3-sulfonyl chloride hydrochloride, tech ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 14-29-34
• Safety Statements: 8-22-26-30-45-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of PYRIDINE-3-SULFONYL CHLORIDE

There total 3 articles about PYRIDINE-3-SULFONYL CHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

3-pyridinesulfonic acid (636-73-7) → pyridine-3-sulfonyl chloride hydrochloride (42899-76-3)

Guidance literature:

3-pyridinesulfonic acid; With phosphorus pentachloride; trichlorophosphate; at 120 ℃;

With hydrogenchloride; In dichloromethane; at 5 ℃; Further stages.;

DOI:10.1002/adsc.200404038

Reference yield:

3-pyridinesulfonic acid (636-73-7) + phosphorus pentachloride (10026-13-8,874483-75-7) → pyridine-3-sulfonyl chloride hydrochloride (42899-76-3)

Guidance literature:

With trichlorophosphate;

Reference yield:

→ pyridine-3-sulfonyl chloride hydrochloride (42899-76-3)

Guidance literature:

upstream raw materials:

3-pyridinesulfonic acid

phosphorus pentachloride

Downstream raw materials:

5-methyl-3-(3-pyridinylsulfonyloxy)phenol

5-phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde

5‐(2-fluorophenyl)‐1‐(pyridine-3-sulfonyl)-1H-pyrrole-3-carbaldehyde

1-(pyridin-3-ylsulfonyl)-5-[2-(trifluoromethyl)phenyl]-1H-pyrrole-3-carbaldehyde

Refernces

• 1、 -. "Proton pump inhibitors". Paragraph 0306. . Retrieved 2015/11/16.
• 2、 -. "Acid secretion inhibitor". Page/Page column 24. . Retrieved 2008/06/13.